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A Dynamic Single-Cell Fragility Test that Assesses Red Blood Cell Membrane Integrity with Applications to Stored Blood

Technology / Case number: #25732
Fang Kong / Subra Suresh / Ming Dao
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Analog AI-Assisted Information Compressor Processor

Technology / Case number: #25685
Ronald Davis
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Uncharted Frontiers, Connected World
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Computationally Engineering Integrase Variants with Improved Activity

Technology / Case number: #25676
Omar Abudayyeh / Jonathan Gootenberg / Kaiyi Jiang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Reliable Gradient-free and Likelihood-free Prompt Tuning

Technology / Case number: #25064J
Prasanna Sattigeri / Subhro Das / Soumya Ghosh / Yuheng Bu / Maohao Shen / Gregory Wornell
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Connected World
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Methods for Detecting Objects-of-Interest in Underwater Environments

Technology / Case number: #19215L
Michael Chan / Daniel Scarafoni / Alexander Bockman
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Connected World
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A Chromatographic Enrichment Platform for the Discovery of Novel Non-Canonical Cell-Penetrating Peptides for Antisense Oligonucleotide Delivery

Technology / Case number: #25261
Bradley Pentelute / Carly Schissel / Charlotte Farquhar
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Loading Classical Data Into a Quantum Computer

Technology, Software / Case number: #20022L
Timothy Braje / John Cortese
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Electronics & Photonics
Impact Areas: Connected World, Advanced Materials
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Chemical Labeling and Identification via Chemical Featurization, Machine Learning, and Graph Analysis

Technology / Case number: #25563
Brett McGuire / Zachary Fried
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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All-to-All Connected Ising Machines with Free-Space Optical Interconnects

Technology / Case number: #21178L
William Herzog / Jeffrey Chou / Suraj Bramhavar / Siddhartha Ghosh
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World
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Improving Statistical Model-Based Speech Enhancement with Deep Neural Networks

Technology / Case number: #21028L
Bengt Borgstrom / Michael Brandstein / Robert Dunn
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World, Advanced Materials
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PRUNE: Prioritizing Risk for Unmitigated Network Exploitables

Technology / Case number: #20440L
Pierre Trepagnier / Dennis Ross / Allan Wollaber
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Connected World
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Daughterless Male Mammals for Population Suppression

Technology / Case number: #21866TE
Kevin Esvelt
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Sustainable Future
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Systems and Approaches for Context-Aware Action Recognition by Dual Attention Network

Technology / Case number: #22125J
Bolei Zhou / Tete Xiao / Quanfu Fan / Dan Gutfreund
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Advanced Materials
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Infrastructure-free NLoS Obstacle Detection for Autonomous Cars

Technology / Case number: #22032J
Daniela Rus / Guy Rosman / Sertac Karaman / Felix Naser / Igor Gilitschenski / Alexander Amini / Christina Liao
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods and Apparatuses to Track Hand Configurations based on Ultrasound Signals

Technology / Case number: #25586
Xuanhe Zhao / Gengxi Lu
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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Methods for Improving Cross-Ancestry Transferability in Predicting Polygenic Phenotypes from Genetic Variation

Technology / Case number: #24858
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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RNAI-Based Method of Screening and Characterizing Drug Combinations

Technology / Case number: #19756
Michael Hemann / Justin Pritchard / Douglas Lauffenburger
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Learning-Guided Electron Microscopy

Technology / Case number: #21380J
Yaron Meirovitch / Aravinathan Samuel / Lu Mi / Jeff Lichtman / Nir Shavit
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living, Uncharted Frontiers
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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