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Fusion Proteins As A Cause For ALS

Technology / Case number: #24280J
Ernest Fraenkel / Ghazaleh Sadri-Vakili / Sali Farhan / Yogindra Raghav / Vakili Khashayar / Tiziana Petrozziello / James Berry / Merit Cudkowicz / Spencer Kim / Allison Dilliott / Michael Talkowski / Dadi Gao / Ricardo Pinto
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Method for Improving Certification-Based Robust Training by Refining Decision Boundary

Technology / Case number: #24050J
Alexandre Megretski / Luca Daniel / Pin-Yu Chen / Subhro Das / Wang Zhang / Lam Minh Nguyen
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Advanced Materials
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Computational Reconfigurable Imaging Spectrometer (CRISP)

Technology / Case number: #19426L
Charles Wynn / Yaron Rachlin / Adam Milstein / Ryan Sullenberger / Sumanth Kaushik
Technology Areas: Agriculture & Food / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Push-Pull Self-Tunneling Belts, Seats, and Slings

Technology / Case number: #25766
Haruhiko Asada
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Analog AI-Assisted Information Compressor Processor

Technology / Case number: #25685
Ronald Davis
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Uncharted Frontiers, Connected World
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Computationally Engineering Integrase Variants with Improved Activity

Technology / Case number: #25676
Omar Abudayyeh / Jonathan Gootenberg / Kaiyi Jiang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Programable Fluidic Chip

Technology / Case number: #25589
Alfredo Alexander-Katz / Guillermo Hernandez-Mendoza
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Ultrawide Field Of View Large Depth-Of-Field Metasurface Assembly For Microendoscopy

Technology / Case number: #25318
Juejun Hu / Tian Gu / Louis Marie Philippe Martin / Zhaoyi Li
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Instrumented Cane that Quantifies Balance Ability

Technology / Case number: #25451
Kaymie Shiozawa / Max Burns / Neville Hogan
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Reliable Gradient-free and Likelihood-free Prompt Tuning

Technology / Case number: #25064J
Prasanna Sattigeri / Subhro Das / Soumya Ghosh / Yuheng Bu / Maohao Shen / Gregory Wornell
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Connected World
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A Neural Network based Dynamical System Modeling Method to Ensure the Contrastively Learned Conservation Laws

Technology / Case number: #24692J
Alexandre Megretski / Luca Daniel / Subhro Das / Wang Zhang / Lam Minh Nguyen
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Uncharted Frontiers, Connected World
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Methods for Detecting Objects-of-Interest in Underwater Environments

Technology / Case number: #19215L
Michael Chan / Daniel Scarafoni / Alexander Bockman
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Connected World
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A Chromatographic Enrichment Platform for the Discovery of Novel Non-Canonical Cell-Penetrating Peptides for Antisense Oligonucleotide Delivery

Technology / Case number: #25261
Bradley Pentelute / Carly Schissel / Charlotte Farquhar
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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System and Method for Post-Hoc Uncertainty Quantification

Technology / Case number: #24904J
Prasanna Sattigeri / Subhro Das / Soumya Ghosh / Yuheng Bu / Maohao Shen / Gregory Wornell
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Uncharted Frontiers, Connected World
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Biodegradable Lipids and Formulations for Intramuscular and Systemic Delivery of mRNA

Technology / Case number: #25351J
Arnab Rudra / Akash Gupta / Kaelan Reed / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Loading Classical Data Into a Quantum Computer

Technology, Software / Case number: #20022L
Timothy Braje / John Cortese
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Electronics & Photonics
Impact Areas: Connected World, Advanced Materials
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Modular System for Lyophilization

Technology / Case number: #22603
Alexander Slocum / Bernhardt Trout
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Chemical Labeling and Identification via Chemical Featurization, Machine Learning, and Graph Analysis

Technology / Case number: #25563
Brett McGuire / Zachary Fried
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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All-to-All Connected Ising Machines with Free-Space Optical Interconnects

Technology / Case number: #21178L
William Herzog / Jeffrey Chou / Suraj Bramhavar / Siddhartha Ghosh
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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