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Intra-Tumoral Injection of Cytotoxic Chemotherapy-Treated Tumor Cells in Combination with Systemic Immune Checkpoint Blockade for Cancer Treatment

Technology / Case number: #21498H
Ganapathy Sriram / Lauren Milling / Darrell Irvine / Michael Yaffe
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Multiplexed in Vivo Disease Sensing with Nucleic Acid-Barcoded Reporters enabling CRISPR-Cas-based Detection

Technology / Case number: #21723H
Liangliang Hao / Renee Zhao / Chayanon Ngambenjawong / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Nanosensors for Detecting and Imaging of Cancer Metastasis

Technology / Case number: #20490H
Liangliang Hao / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Pollen-Like Microstructures

Technology / Case number: #24869
Benedetto Marelli / Muchun Liu
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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Single Molecule Assays for Ultrasensitive Detection of Analytes

Technology / Case number: #24450JY
Tyler Dougan / Connie Wu / David Walt / Richard Novak
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Method for Foam Mitigation Using Hydrophobic Surfaces

Technology / Case number: #19845
Leonid Rapoport / Kripa Varanasi
Technology Areas: Agriculture & Food / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Pressure Compensating Emitter Having Very Low Activation Pressure and Large Operating Range

Technology / Case number: #18187
Amos Winter / Pulkit Shamshery
Technology Areas: Agriculture & Food / Environmental Engineering
Impact Areas: Sustainable Future
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Tiny Nanoparticles for Magnetic Resonance Imaging Applications

Technology / Case number: #18105
He Wei / Oliver Bruns / Eric Hansen / Moungi Bawendi
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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TRAV-005 (Needles) 62/795,857

Technology / Case number: #22144J
Selim Olcum / Robert Kimmerling / David Weinstock / Scott Manalis
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Modified Viscoelastic Assay Rapidly Unmasks Pathological Fibrinolysis Phenotypes in a Wide Spectrum of Human Diseases

Technology / Case number: #19496J
Christopher Barrett / Ernest Moore / Hunter Moore / Michael Yaffe
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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X-Ray Nanoscope

Technology / Case number: #21383
Rajiv Gupta / Richard Lanza / Berthold Horn / Akintunde Akinwande / George Barbastathis
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living, Advanced Materials
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Rapid Droplet-Based Systems for Antibody Drug Discovery

Technology / Case number: #23890J
Brandon DeKosky / Matias Gutierrez Gonzalez / Cheng-yu Chung / Ahmed Fahad / Nicoleen Boyle / Shuyan Jin
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Speckle Assisted Diffusion Imaging

Technology / Case number: #20301
Pranay Jain / Sanjay Sarma
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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High-throughput Electroporation Device

Technology / Case number: #21871
Cullen Buie / Po-Hsun Huang / Sijie Chen
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Single Cell Super-Resolution Proteomics

Technology / Case number: #24088
Mark Harnett / Dimitra Vardalaki
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Targeting Lung Microbiota and its Responding Immune Pathways for Lung Cancer Treatment

Technology / Case number: #20602HRJ
Paul Blainey / Chengcheng Jin / Georgia Lagoudas / Tyler Jacks
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Programmable RNA Writing with the Novel RNA-Guided RNA-Targeting CRISPR-Cas7-11 Enzyme

Technology / Case number: #24072
Omar Abudayyeh / Jonathan Gootenberg / Wenyuan Zhou / Cian Schmitt-Ulms / Alisan Kayabolen
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure and Engineering of the Type III-E CRISPR-Cas7-11 Effector Complex

Technology / Case number: #23945J
Omar Abudayyeh / Jonathan Gootenberg / Wenyuan Zhou / Hiroshi Nishimasu / Kazuki Kato / Cian Schmitt-Ulms
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Polymeric Solid-State MRI Contrast Agents for pH Quantification

Technology / Case number: #18380
Michael Cima / Gregory Ekchian
Technology Areas: Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Transcriptional Sensor for Bile Acids in Bacteroides Thetaiotaomicron

Technology / Case number: #18573
Christopher Voigt / Mao Taketani
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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