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Computationally Engineering Integrase Variants with Improved Activity

Technology / Case number: #25676
Omar Abudayyeh / Jonathan Gootenberg / Kaiyi Jiang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Programable Fluidic Chip

Technology / Case number: #25589
Alfredo Alexander-Katz / Guillermo Hernandez-Mendoza
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Ultrawide Field Of View Large Depth-Of-Field Metasurface Assembly For Microendoscopy

Technology / Case number: #25318
Juejun Hu / Tian Gu / Louis Marie Philippe Martin / Zhaoyi Li
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Instrumented Cane that Quantifies Balance Ability

Technology / Case number: #25451
Kaymie Shiozawa / Max Burns / Neville Hogan
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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A Chromatographic Enrichment Platform for the Discovery of Novel Non-Canonical Cell-Penetrating Peptides for Antisense Oligonucleotide Delivery

Technology / Case number: #25261
Bradley Pentelute / Carly Schissel / Charlotte Farquhar
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipids and Formulations for Intramuscular and Systemic Delivery of mRNA

Technology / Case number: #25351J
Arnab Rudra / Akash Gupta / Kaelan Reed / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Modular System for Lyophilization

Technology / Case number: #22603
Alexander Slocum / Bernhardt Trout
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Methods for Identifying and Modulating Co-occurant Cellular Phenotypes

Technology / Case number: #19998R
Alexander Shalek / Alex Genshaft / Carly Ziegler / Jeffrey Van Humbeck / Ryan King / No Inventor
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Improving Statistical Model-Based Speech Enhancement with Deep Neural Networks

Technology / Case number: #21028L
Bengt Borgstrom / Michael Brandstein / Robert Dunn
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World, Advanced Materials
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A Stretchable, Wearable Ultrasound Transducer for Wide-Scale Breast Cancer Data Collection

Technology / Case number: #20934TE
Canan Dagdeviren / Lin Zhang
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Real-Time G-Protein Coupled Receptor (GPCR) Linked Bioluminescent Sensing of Biological Targets and Processes

Technology / Case number: #21928L
Scott Wick / Deepak Mishra / Frances Nargi
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Prosthetic Socket with Integrated Surface EMG Sensors and sEMG Processing System

Technology / Case number: #21950TE
Seong Ho Yeon / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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CRISPR-based Diagnostics for Transplantation Medicine

Technology / Case number: #21752J
James Collins / Leonardo Riella / Michael Kaminski
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Daughterless Male Mammals for Population Suppression

Technology / Case number: #21866TE
Kevin Esvelt
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Sustainable Future
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In-Vitro Barrier Tissue Plate

Technology / Case number: #21614L
David Walsh / Christina Zook / Johanna Bobrow / Min Jae Song / Marc Ferrer-Alegre / Sam Michael / Molly Boutin / Yen-Ting Tung / Todd Thorsen
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Vocal Biomarkers of Inflammation in Neurophysiological Systems

Technology / Case number: #22308L
Jeffrey Palmer / Thomas Quatieri / Tanya Talkar
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Radio Frequency Photoacoustic Spectroscopy Concept for Detecting Viral Pathogen

Technology / Case number: #22473LJQ
Jeffrey Karp / Charles Wynn / Anthony Samir / Sumanth Kaushik
Technology Areas: Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
License

Computer-Controlled Ankle-Foot Prosthesis With Series J-Spring Actuation

Technology / Case number: #22922TE
Matthew Carney / Daniel Levine / Matthew Handford / Christopher Williams / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Universal Gastrointestinal Tract Motility Mapping System

Technology / Case number: #24142J
Carlo Giovanni Traverso / Neil Jia
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

A Smart Compression Sleeve for Lymphedema Treatment

Technology / Case number: #24285J
Daniela Rus / Joseph DelPreto / Alphonse Taghian / Cheryl Brunelle
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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