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Immunotherapeutic Approaches Directed at MZB1 for Plasma Cell and B Cell Malignancies

Technology / Case number: #26513J
Jianzhu Chen / Mariateresa Fulciniti / Mehmet Samur / Elena Maroto Martin / Yingjie Zhao / Nikola Ivica / Mikhil Munshi
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Organ on a Chip System

Technology / Case number: #22328
Linda Griffith / Duncan O'Boyle / David L Trumper
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Ultra-Thin Conformal Coating Device for Cell Therapy

Technology / Case number: #26281J
Giovanni Traverso / Henry Trainor / Boram Kim / Jong Seung Lee / Nabil Shalabi / Matt Murphy / Troy Ziliang Kang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A REtrievable IntravaSCUlar Implant SystEm (RESCUE) for Cell Therapy

Technology / Case number: #26283J
Robert Langer / Jong Seung Lee / Matt Murphy / SeungHo Lee / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Rare Earth Spatial/Spectral Barcodes for Multiplexed Biochemical Testing

Technology / Case number: #15231L
Patrick Doyle / Ji Seok Lee / Paul Bisso / Albert Swiston
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living, Advanced Materials
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Peptide-Polyanion Conjugate to Activate STING Innate Immune Signaling

Technology / Case number: #26286
Paula Hammond / Justin Kaskow
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Emulsion Agglutination Assay for Sensing of Zika Virus

Technology / Case number: #20574Q
Timothy Manning Swager / Kosuke Yoshinaga / Ki-Joo Sung / Lukas Zeininger / Eric Miller / Qifan Zhang / Hadley Sikes
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Robert Langer / Linzixuan Rhoda Zhang / Ruiqing Xiao / Ana Jaklenec
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Method and Apparatus for High Throughput Diagnosis of Diseased Cells With Microchannel Devices

Technology / Case number: #11937
Subra Suresh / Scott Manalis
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Volume Contraction and Substrate Fluidization as a Means to Reduce Drag on Bodies Moving Through a Granular Substrate

Technology / Case number: #13498
Alexander Slocum / Amos Winter / Anette Hosoi
Technology Areas: Agriculture & Food / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Method for Quantitative Monitoring of In Vivo Tumor Oxygenation

Technology / Case number: #19207JQ
Michael Cima / Ehud Schmidt / Robert Cormack / Larissa Lee / Gregory Ekchian
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Yubin Cai / Troy Ziliang Kang / Ming Zhao / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Amplitude Spectroscopy of a Solid-State Artificial Atom

Technology / Case number: #13407L
Karl Berggren / William Oliver
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Deepak Subramanian / Rajib Dey / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Discovery and Engineering of Novel Integrases for High-Efficiency Gene Integration

Technology / Case number: #23554
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Flow Cytometry with Mass Sensitive Readout

Technology / Case number: #12273J
Scott Manalis
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Raman Spectroscopy Based Sensitive and Specific Detection of Alternate Glycemic Markers, Glycated Hemoglobin (HbA1c) and Glycated Albumin for Longterm Diabetes Monitoring

Technology / Case number: #15295
Ramachandra Dasari / Jeon Woong Kang / Narahara Dingari / Ishan Barman
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Imidazole-Based Random Co-Polymer for Synthesis of Water Soluble Biocompatible Semiconductor Nanocrystals

Technology / Case number: #13877
Moungi G Bawendi / Numpon Insin
Technology Areas: Chemicals & Materials / Diagnostics / Electronics & Photonics
Impact Areas: Healthy Living
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Heterocycle-Modified Quinolines for Fluorescence-Based Protein Kinase Sensing

Technology / Case number: #13876
Barbara Imperiali
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Robert Langer / Rosemary Kanasty / Matthew Webber / Kun Xue / Hung-Chieh (Danny) Chou / Benjamin Tang / Yunlong Zhang / Yair Levi / Arturo Vegas / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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