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Micro-Invasive Neural System for Delivering Antiseizure Medications to the Epileptic Focus for the Treatment of Refractory Epilepsy

Technology / Case number: #25721J
Michael Cima / Peter West / Karen Wilcox / Cameron Metcalf / Hannah Jackson / Max Cotler
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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One-Step Construction of Allogeneic CAR-NK Cells with Increased Anti-Tumor Cytotoxicity and Resistant to Rejection by Host T Cells and NK Cells

Technology / Case number: #25757J
Jianzhu Chen / Fuguo Liu / Rizwan Romee
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Pulsing Light to Promote Recovery from Amblyopia

Technology / Case number: #25767P
Mark Bear / Francis Reilly-Andujar
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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FISHTALE- Fluorescent In Situ Hybridization of TAL Effectors

Technology / Case number: #19813TE
Edward Stuart Boyden / Nicholas Barry / Samuel Rodriques / Adam Marblestone
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Noreen Wauford / Breanna DiAndreth
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Therapeutic Strategy for Rett Syndrome and Autism Spectrum Disorders

Technology / Case number: #12720WPJ
Rudolf Jaenisch / Emanuela Giacometti / Daniela Tropea / Nathan Wilson / Mriganka Sur
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Ram Sasisekharan / Devin Quinlan / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Artificially Engineered Protein Hydrogels to Mimic Nucleoporin Selective Gating

Technology / Case number: #17166
Bradley D. Olsen / Minkyu Kim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Zwitterionic Polymer Functionalized Lipid Nanoparticles for Delivery of mRNA

Technology / Case number: #24662
Robert Langer / Sushil Lathwal / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Robocap

Technology / Case number: #24836J
Robert Langer / Amro Alshareef / Shriya Sruthi Srinivasan / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Combined 40Hz Stimulation and Dexmedetomidine Therapy for Alzheimers Disease and Neuronal Degeneration

Technology / Case number: #25176PJ
Li-Huei Tsai / Oluwaseun Johnson-Akeju / Jordan Harrod / Diane Chan / Emery N Brown
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Modular MicroRNA Expression from Self-Replicating RNA (Replicons)

Technology / Case number: #25464
Ron Weiss / Tea Crnkovic
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Boron-Containing Pharmacophore

Technology / Case number: #21111
Ronald T Raines / Brian Graham / Ian Windsor
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #15299J
Alice Ting / David Baker / Florian Richter / Lucas Nivon / Daniel Liu
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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DIAL: Programmable Promoter Editing to Generate Defined, Heritable Setpoints of Gene Expression

Technology / Case number: #25874
Katie Galloway / Yunbeen Bae / Sneha Kabaria
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Peptide-Targeted Layer-by-Layer Nanoparticle for Glioblastoma Treatment

Technology / Case number: #25659
Paula Hammond / Priya Ganesh / Andrew Pickering / Nicholas Lamson / Natalie Boehnke
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Conformable Ultrasound Face Patch for Cavitation Enhanced Transdermal

Technology / Case number: #24824TE
Canan Dagdeviren
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Enhanced Differentiation to Endodermal Derivatives with Modulated Oxygen Level

Technology / Case number: #15589
Clark Colton / Amanda Diienno / Jeffrey Millman
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Fusion Proteins As A Cause For ALS

Technology / Case number: #24280J
Ernest Fraenkel / Ricardo Pinto / Dadi Gao / Michael Talkowski / Allison Dilliott / Spencer Kim / Merit Cudkowicz / James Berry / Tiziana Petrozziello / Vakili Khashayar / Yogindra Raghav / Sali Farhan / Ghazaleh Sadri-Vakili
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Phosphorylation-Based miRNA High Sensor

Technology / Case number: #19683
Ron Weiss / Ross Jones / Jin Huh
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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