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DNA Instructional Model

Technology / Case number: #17291
J. Kim Vandiver / Kathleen Mead Vandiver / Bethany Lemanski
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Self-Assembled (Poly-(L-Glutamic Acid-PEG-Drug)-PLGA Micelles for Multistage Nanoparticle Delivery System

Technology / Case number: #14877J
Moungi G Bawendi / Dai Fukumura / Cliff Wong / Rakesh K. Jain
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Develop New Lethal Mutagens for Viral Diseases

Technology / Case number: #16089
John M Essigmann / Katherine Silvestre / Deyu Li
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Brian Belmont / Michael Marletta / Jacquin Niles / Stephen Goldfless
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Dendrimer and Peptide Based Excipients for the Attenuation of Protein Aggregation

Technology / Case number: #14184
Bernhardt Trout / Diwakar Shukla / Curtiss Schneider
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Therapeutics
Impact Areas: Healthy Living
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The Design of DNA-scaffolded Subunit Vaccines for Enhanced Germinal Center Responses in HIV Vaccination

Technology / Case number: #25982H
Darrell J Irvine / Anna Romanov / Grant Knappe / Mark Bathe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Advanced Materials
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Sangeeta Bhatia / Yin Ren
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Darrell J Irvine / Dana Al Sulaiman / Sylvain Ladame / Yin Hao Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of a Platform to Noninvasively Image Car T Cells

Technology / Case number: #25905J
Michael Hemann / Julia Froese / Ali Salehi / Taha Rakhshandehroo / Jennifer Rowley / Mohammad Rashidian
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Fast Nonlinear Dynamic Electrochemical Characterization of Arbitrary Fluids

Technology / Case number: #24656
Ian Hunter / Billal Iqbal / Kimberley Cheng / Michael Aling
Technology Areas: Agriculture & Food / Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Vaccine Targeting to Mucosal Lymphoid Tissues in the Gastrointestinal Tract

Technology / Case number: #25463H
Darrell J Irvine / Ozgun Kocabiyik
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Micro-Invasive Neural System for Delivering Antiseizure Medications to the Epileptic Focus for the Treatment of Refractory Epilepsy

Technology / Case number: #25721J
Michael Cima / Peter West / Karen Wilcox / Cameron Metcalf / Hannah Jackson / Max Cotler
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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One-Step Construction of Allogeneic CAR-NK Cells with Increased Anti-Tumor Cytotoxicity and Resistant to Rejection by Host T Cells and NK Cells

Technology / Case number: #25757J
Jianzhu Chen / Fuguo Liu / Rizwan Romee
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Pulsing Light to Promote Recovery from Amblyopia

Technology / Case number: #25767P
Mark Bear / Francis Reilly-Andujar
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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FISHTALE- Fluorescent In Situ Hybridization of TAL Effectors

Technology / Case number: #19813TE
Edward Stuart Boyden / Nicholas Barry / Samuel Rodriques / Adam Marblestone
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Noreen Wauford / Breanna DiAndreth
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Therapeutic Strategy for Rett Syndrome and Autism Spectrum Disorders

Technology / Case number: #12720WPJ
Rudolf Jaenisch / Emanuela Giacometti / Daniela Tropea / Nathan Wilson / Mriganka Sur
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Ram Sasisekharan / Devin Quinlan / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Artificially Engineered Protein Hydrogels to Mimic Nucleoporin Selective Gating

Technology / Case number: #17166
Bradley D. Olsen / Minkyu Kim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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