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Nano-Fibular Nanoparticle Polymer-Drug Conjugate for Sustained Dermal Delivery of Retinoids

Technology / Case number: #17491
Paula Hammond / Mohiuddin Quadir / Steven Castleberry
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living
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Layer-by-Layer Nanoparticles for Cytokine Therapy in Cancer Treatment

Technology / Case number: #20027H
Darrell J Irvine / Talar Tokatlian / Santiago Correa Echavarria / Antonio Barberio / Mariane Melo / Erik Dreaden / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Methods and Compositions for Increasing Sensitivity of Cancer Cells to Glutaminase Inhibitors and Applications to Cancer Therapy

Technology / Case number: #19305
Matthew Vander Heiden / Laura Danai / Alexander Muir / Dan Gui
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Intracellular Calcium Sensors for MRI

Technology / Case number: #20143
Alan Pradip Jasanoff / Benjamin Bartelle / Ali Barandov
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Dendrimer Drug Conjugates for Sustained Intra-Articular Delivery

Technology / Case number: #19214
Paula Hammond / Brett Geiger
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods for Gene Delivery with Papillomaviruses

Technology / Case number: #21704
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Procedural Sedation Monitoring: Systems and Methods for Predicting Adverse Events and Assesing Level of Sedation

Technology / Case number: #17704J
George Verghese / Margaret Guo / Baruch Krauss / Rebecca Asher / Thomas Heldt
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Mcl-1

Technology / Case number: #17695J
Amy Keating / Loren Walensky / Greg Bird / Raheleh Rezaei Araghi
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Non-Invasive Assessment of Venous Pressure via Actuation of Reciprocal Surface Forces for Vessel Collapse Using Single-Crystal Ultrasound in Vertebrates

Technology / Case number: #19192QJ
Brian Anthony / Athena Huang / Jason Yang / Maulik Majmudar / Zijun Wei / Robin Singh / Alexander Jaffe / Mohamad Ali Najia / Galit H. Frydman / Aaron Zakrzewski
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Nitroxide-Based Macromolecular Contrast Agents with Unprecedented Transverse Relaxivity and Stability for Magnetic Resonance Imaging of Tumors

Technology / Case number: #19540J
Jeremiah A. Johnson / Andrzej Rajca / Hung Nguyen
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Removal of Ruthenium-Initiator from Brush-Arm Star Polymers (BASPs) via Core-to-Surface Ring-Opening Methathesis Polymerization (ROMP)

Technology / Case number: #19525
Jeremiah A. Johnson / Matthew Golder
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Sensitization of Bacterial Cells to Quinolone Antibiotic by Restoring High Energy Producing Metabolism

Technology / Case number: #20096
James Collins / Arnaud Gutierrez / Michael Lobritz
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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GLYCAN-BINDING PROTEINS AND RELATED COMPOSITIONS AND METHODS

Technology / Case number: #21107
Barbara Imperiali / Elizabeth Ward / Cristina Cella
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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RNA-Based Regulatory Technologies for Improved miRNA Sensors

Technology / Case number: #19686
Ron Weiss / Jin Huh / Kevin Lebo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Bfl-1

Technology / Case number: #18607
Amy Keating / Justin Jenson
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Mucins as Regulators of Interspecies Microbial Interactions

Technology / Case number: #17408
Katharina Ribbeck / Julia Co / Erica Shapiro / Nicole Kavanaugh
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Fine-Tuning pKa's of Nucleoside Analogs to Increase Mutagenicity; a Strategy to Develop More Potent Lethal Mutagen with Anti-Viral or Anticancer Properties

Technology / Case number: #17657
John M Essigmann / Sam Peng / Vipender Singh / Bogdan I Fedeles / Andrei Tokmakoff
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Designing Universal Influenza Medical Countermeasures

Technology / Case number: #22030L
Darrell Ricke
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Model-based Control for Column-based Continuous Viral Inactivation of Biopharmaceuticals

Technology / Case number: #21959
Richard D Braatz / Moo Sun Hong / Amos Lu
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Structured DNA Nanoparticle Platform for Protein- and Peptide-based Vaccines

Technology / Case number: #20929H
Darrell J Irvine / Benjamin Read / Eike-Christian Wamhoff / Tyson Moyer / Rebecca Du / Remi Veneziano / Mark Bathe
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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