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A Synthetic Nanotube Antibody for Selective Molecular Recognition

Technology / Case number: #14090
Michael S. Strano / Jong Ho Kim / Paul Barone / Daniel Heller / Jingqing Zhang
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Anti-Sigmas for Programmable Transcriptional Regulation

Technology / Case number: #15523J
Christopher Voigt / Virgil Rhodius / Carol Gross
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Novel Recombinases and Target Sequences

Technology / Case number: #17809J
Ron Weiss / Yinqing Li / Xavier Duportet / Gregory Batt
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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RNA Engineering for CRISPR Synthetic Circuits and Endogenous Regulation

Technology / Case number: #16876
Timothy K Lu / Samuel Perli / Lior Nissim
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Covalently Functionalized Hydrogels on Oxygen Permeable Membranes for Stable, Scalable, and Xeno Free Growth of Undifferentiated Human Embryonic Stem Cells

Technology / Case number: #16162
Anna Coclite / Amanda Diienno / Karen Gleason / Clark Colton
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Extra Cellular Matrix Proteins and Cancer

Technology / Case number: #15501JHR
Steven Carr / Richard Hynes / Alexandra Naba / Karl Clauser / Kenneth Tanabe
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Cytosolically-Active Peroxidases as Reporters for Electron Microscopy

Technology / Case number: #15128
Jeffrey Martell / Alice Ting
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Methods for Cell Separation and Cytometry Based on Directed Cell Rolling on Patterned Substrates

Technology / Case number: #12899
Jeffrey Michael Karp / Seungpyo Hong / Rohit N Karnik / Ying Mei / Suman Bose / Robert Langer / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids

Technology / Case number: #16016J
Mo Movassaghi / Nicolas Boyer / Justin Kim / Paul Hergenrother / Karen Morrison
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Justin Lim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Brian Belmont / Stephen Goldfless / Jacquin Niles / Michael Marletta
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The Design of DNA-scaffolded Subunit Vaccines for Enhanced Germinal Center Responses in HIV Vaccination

Technology / Case number: #25982H
Mark Bathe / Grant Knappe / Anna Romanov / Darrell J Irvine
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Advanced Materials
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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Yin Hao Chang / Sylvain Ladame / Dana Al Sulaiman / Darrell J Irvine
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Applications of Streptococcus-derived Cas9 Nucleases on Minimal A-Rich PAM Targets

Technology / Case number: #20491XTE
Noah Jakimo / Lisa Nip / Pranam Chatterjee / Joseph Jacobson
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Full-field Optical Coherence Microscopy System Using a Digital Focal Plane Array

Technology / Case number: #24144LJ
Joseph Gardecki / Matthew Johnson / Osman Ahsen / Michael Bradshaw / Guillermo Tearney
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Fast Nonlinear Dynamic Electrochemical Characterization of Arbitrary Fluids

Technology / Case number: #24656
Michael Aling / Kimberley Cheng / Billal Iqbal / Ian Hunter
Technology Areas: Agriculture & Food / Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Kannan Tharakaraman / Vidya Subramanian / Devin Quinlan / Ram Sasisekharan
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Boron-Containing Pharmacophore

Technology / Case number: #21111
Ronald T Raines / Ian Windsor / Brian Graham
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods of Breeding, Maintaining, and Releasing Wild-Like Organisms with Desired Genetics

Technology / Case number: #20965TEJ
Kevin Esvelt / Sam Telford III
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Sustainable Future
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Novel Short Tandem Repeats (STRs) Analysis Methods

Technology / Case number: #18500L
Edward Wack / Anna Shcherbina / Brian Helfer / Darrell Ricke / Joseph Isaacson / Adam Michaleas / Philip Fremont-Smith / James Watkins / James Harper / Martha Petrovick / Eric Schwoebel
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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