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Micro-Invasive Neural System for Delivering Antiseizure Medications to the Epileptic Focus for the Treatment of Refractory Epilepsy

Technology / Case number: #25721J
Michael Cima / Max Cotler / Hannah Jackson / Cameron Metcalf / Karen Wilcox / Peter West
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Vaccine Targeting to Mucosal Lymphoid Tissues in the Gastrointestinal Tract

Technology / Case number: #25463H
Ozgun Kocabiyik / Darrell Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Fast Nonlinear Dynamic Electrochemical Characterization of Arbitrary Fluids

Technology / Case number: #24656
Michael Aling / Kimberley Cheng / Ian Hunter
Technology Areas: Agriculture & Food / Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Scalable and High throughput Assembly of Layer-by-Layer Nanoparticles

Technology / Case number: #25554H
Ivan Susin Pires / Darrell Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Modular MicroRNA Expression from Self-Replicating RNA (Replicons)

Technology / Case number: #25464
Ron Weiss / Tea Crnkovic
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Robocap

Technology / Case number: #24836J
Carlo Giovanni Traverso / Shriya Srinivasan / Robert Langer / Amro Alshareef
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Zwitterionic Polymer Functionalized Lipid Nanoparticles for Delivery of mRNA

Technology / Case number: #24662
Robert Langer / Allen Jiang / Sushil Lathwal / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Boron-Containing Pharmacophore

Technology / Case number: #21111
Ronald Raines / Ian Windsor / Brian Graham
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Single-Step Insertion into Repeated Regions for Efficient Multi-Locus Assortment and Daisyfield Drive

Technology / Case number: #19136TJE
Kevin Esvelt / Jianghong Min / Charleston Noble
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Novel Short Tandem Repeats (STRs) Analysis Methods

Technology / Case number: #18500L
Edward Wack / Anna Shcherbina / Brian Helfer / Darrell Ricke / Joseph Isaacson / Adam Michaleas / Philip Fremont-Smith / James Watkins / James Harper / Martha Petrovick / Eric Schwoebel
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Synthetic Hydrogels for Stem Cell Propagation and Organogenesis

Technology / Case number: #20047
Linda Griffith
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Conformable Ultrasound Face Patch for Cavitation Enhanced Transdermal

Technology / Case number: #24824TE
Canan Dagdeviren
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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SpongeBot: Programmable Solution Providing Unmatched Protection Against Pandemics

Technology / Case number: #22349J
Ron Weiss / Jin Huh / Yingzhong Li / Hava Siegelmann / Eric Goldstein
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Systems And Assays for Identifying Pu.1 Inhibitors

Technology / Case number: #23154PJ
Li-Huei Tsai / William Ralvenius / Barbara Czako
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Two Person Mixture Deconvolution for Application with ForenSeq Kintelligence Workflow

Technology / Case number: #24078L
Philip Fremont-Smith / Chelsea Lennartz / Natalie Damaso
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Dynamic Single-Cell Fragility Test that Assesses Red Blood Cell Membrane Integrity with Applications to Stored Blood

Technology / Case number: #25732
Fang Kong / Subra Suresh / Ming Dao
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Computationally Engineering Integrase Variants with Improved Activity

Technology / Case number: #25676
Omar Abudayyeh / Jonathan Gootenberg / Kaiyi Jiang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Chromatographic Enrichment Platform for the Discovery of Novel Non-Canonical Cell-Penetrating Peptides for Antisense Oligonucleotide Delivery

Technology / Case number: #25261
Bradley Pentelute / Carly Schissel / Charlotte Farquhar
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipids and Formulations for Intramuscular and Systemic Delivery of mRNA

Technology / Case number: #25351J
Arnab Rudra / Akash Gupta / Kaelan Reed / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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