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Non-Invasive Sensory Stimulation Modifies the Microbiome-Gut-Brain Axis and Engages Insular-Vagal Circuitry

Technology / Case number: #25760P
Li-Huei Tsai / Jung Park / Ravikiran Raju / Cheng-Yi Yang / Lorenzo Bozzelli / Daniela Rodrigues Amorim
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Supramolecular PEGylation of Protein Therapeutics

Technology / Case number: #18077
Robert Langer / Eric Appel / Matthew Webber / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Collapsible Library Design to Enable Characterization of Hyperdiverse Peptide Libraries

Technology / Case number: #26377J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Operational Amplifier based Modified Armstrong Oscillator (OAMAO)

Technology / Case number: #25698J
Brian L Wardle / Aniruddha Ghosh / Haim Primo / Yosef (Yosi) Stein / Luiz Henrique Acauan
Technology Areas: Electronics & Photonics / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Connected World
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Robust Multi-Modal Tactile Sensor for Contact-Rich Manipulation Using Tactile-Diffusion Policies

Technology / Case number: #26475J
Edward Adelson / Naveen Kuppuswamy / Alan Zhao / Benjamin Burchfiel / Siyuan Feng / Russell Louis Tedrake
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Connected World
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Stent Design that Controls Internal Stress Distribution to Reduce Peak Stress and Minimize Microstructural Ordering Impact

Technology / Case number: #26143J
Elazer R Edelman / Francesc Canalejo Codina / Andres Garcia Granada / Jordi Martorell Lopez / Mercedes Balcells-Camps
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Platform for Label-Free Recording/Imaging Metabolic Activity and Status in Cells

Technology / Case number: #25931P
W. David Lee / Rebecca Zubajlo / Tatsuya Osaki / Xiang (Shawn) Zhang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Enhanced Sintering Process by Ball-Milling

Technology / Case number: #16073
Christopher Schuh / Mansoo Park
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Machine Learned Chemical Intuition for the AI Generation of Molecules within Specific Chemical Spaces

Technology / Case number: #26403
Brett McGuire / Zachary Fried
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Sub-13.5 nm Projection Lithography System and Components

Technology / Case number: #26289L
Mordechai Rothschild / Paul Chesler / Nate O'Connor / Peter Moulton / Tommy Sebastian / Vladimir Liberman
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation
Impact Areas: Connected World, Advanced Materials
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Seqwell Ancillary Tools and Assays Including StimSeq and Spatial Barcoding

Technology / Case number: #19508
J. Christopher Love / Marc Wadsworth / Travis Hughes / Alex Shalek / Todd Gierahn
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Robert Langer / Vikash Pal Singh Chauhan / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Automated Flow Synthesis of Combinatorial Protein Libraries

Technology / Case number: #26382J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Silicone Valve API Compartment Sealing Barrier

Technology / Case number: #21569QJ
Giovanni Traverso / Brian Jensen / Mikkel Oliver Jespersen / Morten Frederiksen / Alex Abramson
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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High Efficiency 3-Coil Coreless Power Transformer

Technology / Case number: #25633
Chathan M Cooke / Noah Salk
Technology Areas: Electronics & Photonics / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Grooved, Nested-Cylinder, Layer-Wound Superconducting Magnets and Related Construction Techniques

Technology / Case number: #26125
Brian Labombard / Samuel Austin / Theodore Mouratidis
Technology Areas: Chemicals & Materials / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Low-Cost Air Particulate Monitor Based on Particle Capture and Imaging

Technology / Case number: #19213
Rohit N Karnik / An Chang
Technology Areas: Environmental Engineering / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future, Connected World
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Embedded Hard-Stop Interconnect Spacers for 3D/Flip-Chip Integrated Superconducting Qubit Module

Technology / Case number: #26145L
William Oliver / Bethany Huffman / David Kim / Mollie Schwartz / Jonilyn Yoder / Rabindra Das
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation
Impact Areas: Connected World
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Spring-Loaded Double Pentograph (SLDP) Mechanism for Human Balancing and Weight Support

Technology / Case number: #25811
Harry Asada / Ravi Tejwani
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Michael Yaffe / Jesse C Patterson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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