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Hardware Models of Biochemical Reaction Networks

Technology / Case number: #13076
Rahul Sarpeshkar
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Colloidal Hydrogel Particles with tunable Chemistry, Geometry, and Flexibility

Technology / Case number: #13461J
Patrick Doyle / Daniel Pregibon / Ramin Haghgooie / Mehmet Toner
Technology Areas: Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction from Cellulosic Materials

Technology / Case number: #15695
Mitchell Tai / Gregory Stephanopoulos
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
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Methods for Microbial Oil Overproduction via Amplification of the Biosynthetic and Sequestration Pathways Individually or in Combination

Technology / Case number: #15152
Mitchell Tai / Sagar Chakraborty / Gregory Stephanopoulos
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Gizem Akcay / R. Collier
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Arturo Vegas / Yair Levi / Yunlong Zhang / Benjamin Tang / Hung-Chieh (Danny) Chou / Kun Xue / Matthew Webber / Rosemary Kanasty / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Distinct Gene Systems Mediating Activity-Dependent Plasticity in Visual Cortex

Technology / Case number: #11841P
Shayan Mukherjee / Daniela Tropea / Gabriel Kreiman / Mriganka Sur / Alvin Lyckman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Oscillating Cell Culture Bioreactor

Technology / Case number: #12301
Matteo Moretti / Robert Langer / Lisa Freed
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Glucose Valve and Other Metabolite Valves

Technology / Case number: #12369
Tae Moon / Kristala L Jones Prather / Kevin Solomon
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Reverse Micelle Nanoprecipitation: A Method for Encapsulating Nucleic Acids in Biodegradable Polymers

Technology / Case number: #12561J
Aleksandar Radovic-Moreno / Liangfang Zhang / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Computer Science / Electronics & Photonics
Impact Areas: Healthy Living, Advanced Materials
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Olfactory Receptor-Based Devices

Technology / Case number: #12776TE
Manu Prakash / Andreas Mershin / Brian Cook / Joanke (Johanna) Bikker Graveland / Liselotte Kaiser / Shuguang Zhang / Yael Maguire / David Kong
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Transcriptional Engineering of Lactobacillus for Improved Lactic Acid Tolerance and Productivity at Low pH

Technology / Case number: #12783
Daniel Klein-Marcuschamer / Gregory Stephanopoulos
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
David Feldser / Leah Schmidt / Tyler Jacks
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Extension of a Finite Element Framework for Calculation of DNA Nanostructure Solution Shape, Mechanical, and Optical Properties

Technology / Case number: #16421
Mark Bathe / Do-Nyun Kim / Matthew Adendorff / Keyao Pan / Lun Yang / Reza Sharifi Sedeh / Etienne Boulais / Oskar Hallatschek / Klaus-Jurgen Bathe
Technology Areas: Computer Science
Impact Areas: Healthy Living
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Normalization Correction for Inter-Detector Scatter Enhanced Positron Emission Tomography

Technology / Case number: #16136
Shivang Dave / Vicente Parot / Eduardo Lage / Joaquin Herraiz
Technology Areas: Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Methods for Increasing Safety of Embryonic Stem Cells

Technology / Case number: #13769
Jeffrey Millman / Clark Colton
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods for Enhanced Production of Cardiomyocytes From Embryonic Stem Cells

Technology / Case number: #12777
Daryl Powers / Jeffrey Millman / Amanda Diienno / Clark Colton
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods of Controlled Self-Renewal and Differentiation of Intestinal Stem Cells

Technology / Case number: #15728J
Jeffrey Michael Karp / Xiaolei Yin / Marc Succi / Robert Langer
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Engineering DNA Assembly in Vivo and Knock Down of Gene Expression Using the Reverse Transcriptase Activity

Technology / Case number: #16593
Christopher Voigt / Johann Elbaz
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Microbial Production of 3,4-Dihydroxybutyrate (DHBA) and 3-Hydroxybutyrolactone (3-HBL) from Glucose

Technology / Case number: #14595
Kristala L Jones Prather / Collin Martin / Himanshu Dhamankar
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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