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Synthesis of Covalent Protein Dimers that can Inhibit MYC-Driven Transcription

Technology / Case number: #23305WJ
Stephen Buchwald / Charles Li / Susana Hawken / Ann Boija / Muhammad Jbara / Jacob Rodriguez / Andrei Loas / Sebastian Pomplun / Carly Schissel / Isaac Klein / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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RNA-Loaded Lipid Nanoparticle (LNP)

Technology, Tangible Property / Case number: #24973H
Darrell J Irvine / B.j. Kim
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Target for Modulating Body Mass

Technology / Case number: #21326
Jianzhu Chen / Ting Dong / Yingzhong Li / Nikola Ivica
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Composition and Methods to Generate Assymetric Bispecific Antibodies from a Single Cell Line

Technology / Case number: #17698
Ram Sasisekharan / Andrew Hatas / Eduardo Fleischer / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Amphiphilic Cisplatin Prodrug Nanoparticles for Co-Incorporation of Water-Insoluble Synergistic Small Molecules Chemotherapies and RNAi

Technology / Case number: #17774
Paiman Ghoroghchian / Ting Li / Ruogu Qi / Haihua Xiao
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Microfluidic Device for the 3D and Compartmentalized Coculture of Neuronal and Muscle Cells, with Functional Force Readout

Technology / Case number: #18042
Roger Kamm / Sebastien Uzel
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Microbial System for Biosynthesis of Natural and Engineered Products Coupled to in Situ Extraction in Supercritical CO2

Technology / Case number: #18721
Kristala L Jones Prather / Michael Timko / Jason Boock / Adam Freedman / Kyle Peet / Janelle Thompson
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future
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Particle Isolation/Enrichment Using Continuous Closed-Loop Spiral Microfluidics

Technology / Case number: #18940
Jongyoon Han / Hyunryul Ryu / Kyungyong Choi
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Transfemoral Rotator Using Push Button Spring Clips

Technology / Case number: #19081
Matthew Cavuto / Matthew Chun
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Optical Methods Level Sensor for Use in a Bioreactor

Technology / Case number: #19143
J. Christopher Love / Amos Lu / Craig Mascarenhas / Richard D Braatz
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Platform for High-Resolution Genome Mapping

Technology / Case number: #19244
Rajeev Ram / Huaiyu Meng
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Electronics & Photonics
Impact Areas: Healthy Living
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Compact Proton Beam Energy Modulator

Technology / Case number: #19382
Matthew Cavuto / Melissa Li / Nathaniel Rodman / Neerja Aggarwal
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Single-Sided Magnets for Remote NMR Measurements

Technology / Case number: #19511
Michael Cima / Ashvin Bashyam / Matthew Li
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Optical Imaging Device

Technology / Case number: #19531
James Fujimoto / Michael Giacomelli / Zhao Wang / Hsiang-Chieh Lee / Osman Ahsen / Kaicheng Liang
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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USpring Design for Prosthetic Applications

Technology / Case number: #19539
Amos Winter / Victor Prost / Kathryn Olesnavage
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Locking and Damping Mechanism for a Prosthetic Knee Joint

Technology / Case number: #19545
Amos Winter / Youngjun Joh / Athena Huang / Jason Fischman / Venkata Narayana Murthy Arelekatti
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Optimized compliant prosthetic foot

Technology / Case number: #19607
Amos Winter / Kathryn Olesnavage
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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A Technique for Imaging Cortical Bone and Soft Tissue Using the Level-Set Method to Regularize Travel-Time and Full Waveform Tomography Techniques

Technology / Case number: #19710
Brian Anthony / Jonathan Fincke
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Thermally and Electrically Actuated, Heat and Strain Programmable and Sensing,Kilometer-long Micro and Nano, Organic Artificial Muscle Fibers

Technology / Case number: #20097
Polina Anikeeva / Mehmet Kanik
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Implantable Active Coil-based Transducers (ImpACTs) for Minimally-Invasive Biophysical Imaging

Technology / Case number: #20183
Alan Pradip Jasanoff / Aviad Hai / Virginia Spanoudaki
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Electronics & Photonics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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