Micromolded Particles for Cancer Treatment
Microparticulate compositions and methods for delivery and pulsatile release of one or more sting agonists and/or receptors have been developed. The compositions include polymeric microdevices formed from biodegradable and biocompatible polymers or co-polymers thereof including a shell and compartment(s) or discrete regions in the compartment(s) formed by an additive process such as micromolding, three-dimensional printing and lithography. The compositions include microdevices that release individual doses of incorporated STING agonist and/or receptors at defined times, for example, in pulses up to several months after administration with essentially no leakage between releases.
Researchers
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compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
United States of America | Published application -
compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
Australia | Granted | 2,021,270,750 -
compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
Canada | Published application -
compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
China | Published application -
compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
European Patent Convention | Published application -
compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
Israel | Pending -
compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
Japan | Published application -
compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
Mexico | Pending -
compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
New Zealand | Pending -
compositions of polymeric microdevices and methods of use thereof in cancer immunotherapy
South Africa | Pending
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