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Compositions for the Conditional Delivery of Macromolecules and Combination Therapeutics

Technology / Case number: #24492H
Sangeeta Bhatia / Qian Zhong / Edward Tan / Chayanon Ngambenjawong
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Autocatalytic Base Editing for RNA-Responsive Translational Control

Technology / Case number: #24552YJ
James Collins / Makoto Lalwani / Jonathan C. Chen / Xiaoyu Chen / Kehan Zhang / Nathaniel Tippens / Shiva Razavi / Katherine Ilia / Raphael Gayet
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Temporally Multiplexed Imaging Technology

Technology / Case number: #24554MH
Edward Stuart Boyden / Yong Qian
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Controlled Lipid Self-Assembly for Scalable Manufacturing of Next-Generation Immune Stimulating Complexes

Technology / Case number: #24582H
Darrell J Irvine / Ivan Pires / Paula Hammond
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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High Throughput Stochastic Bio-Molecular Sensor

Exclusively Licensed Technology / Case number: #24610
Ashwin Gopinath / Swathi Manda
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Diagnostics
Impact Areas: Healthy Living

Library-Scale Methods for Antibody Functional Screening

Technology / Case number: #24645
Brandon DeKosky
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Non-Fibrotic Implantable Devices on Diverse Organs

Technology / Case number: #24648
Xuanhe Zhao / Jue Deng / Jingjing Wu / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Cleavable Comonomer Strategy for Accelerating Removal of Gel Nail Polish

Technology / Case number: #24652
Jeremiah A. Johnson / Alexandra Johnson / Leticia Cardoso da Costa / Elisabeth Prince
Technology Areas: Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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System and Methods for Noninvasive Point-of-Care Intracranial Pressure, Intracranial Compliance, and Cerebrovascular Resistance Measurement

Technology / Case number: #24678
Charles Sodini / Syed Imaduddin / Thomas Heldt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Modulating Oncogenic Transcriptional Dysregulation with Small Molecule Chimeric Degraders of Cyclin-Dependent Kinase 9

Technology / Case number: #24831
Angela Koehler / Keisuke Motoyama / Mohammed Toure
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Preferential Crystallization of fullrAAVs in a Hanging Drop Crystallizer as an Alternative Method for Downstream Purification of rAAV-based Gene Therapies

Technology / Case number: #24870
Anthony Sinskey / Vivekananda Bal / Moo Sun Hong / Stacy Springs / Richard D Braatz / Paul Barone
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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A Hybrid Polymeric System for Programmed Drug Release to the Heart

Exclusively Licensed Technology / Case number: #24959
Robert Langer / Erika Wang / Ana Jaklenec
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living

Implantable device to ensure stoma patency following Endoscopic Third Ventriculostomy Procedure

Technology / Case number: #24977
Ellen Roche / Jonas Sog / Gabriel Friedman / Bryce Starr / Luca Rosalia
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Recombinant Transmembrane Domain-Deficient STING as Biomimetic Protein Carrier for cGAMP Enhanced Cancer Immunotherapy

Technology / Case number: #25012
Paula Hammond / Celestine Jia Huey Hong / Shengnan Huang / Yanpu He / Jiahe Li / Angela Belcher
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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In Solution Monoclonal Polony Generation on Inorganic Nanoparticle

Technology / Case number: #25039
Ashwin Gopinath / Emily Wu / Nayan Agarwal
Technology Areas: Chemicals & Materials / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Polystyrene Coated Magnetic Beads Serving as Raman Reporter for Simultaneous Target Binding and Identification

Technology, Tangible Property / Case number: #25081
Loza Tadesse / Nikiwe Mhlanga / Jongwan Lee / Marissa Morales
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Mechanisms for Controlled Volume Injection into a Soft Media with Concurrent Pressure Measurement

Technology / Case number: #25109
Alexander Slocum / Sarah Sams / Andre Pincot / Joseph Morales / Emily Sologuren / Brendan Unikewicz / Tal Cohen / Nevan Hanumara
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Eye Drop Positioning Device with Haptic Feedback

Technology / Case number: #25116
Benjamin Lahner / Jesse George-Akpenyi / Carly Smith / Seung Hyeon Shim
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Strong Adhesion of Wet Conducting Polymers on Diverse Substrates

Technology / Case number: #21093
Xuanhe Zhao / Akihisa Inoue / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Circular, Strained Zymogen

Technology / Case number: #21110J
Ronald T Raines / Ian Windsor
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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