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Scalable Sets of Protein Barcodes for Neural Morphology Measurement and Connectomics

Technology / Case number: #24825MH
Edward Boyden / Samuel Rodriques / Andrew Payne / Bobae An
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Implantable device to ensure stoma patency following Endoscopic Third Ventriculostomy Procedure

Technology / Case number: #24977
Ellen Roche / Luca Rosalia / Bryce Starr / Gabriel Friedman / Jonas Sogbadji
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Recombinant Transmembrane Domain-Deficient STING as Biomimetic Protein Carrier for cGAMP Enhanced Cancer Immunotherapy

Technology / Case number: #25012
Jiahe Li / Yanpu He / Shengnan Huang / Celestine Jia Huey Hong / Paula Hammond / Angela Belcher
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Tool for Spatially Targeted Access and Placement of Hardware or Drugs in Deep or Consolidated Tissues

Technology / Case number: #25071
Shriya Srinivasan / Robert Langer / Alexander Madinger
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Polystyrene Coated Magnetic Beads Serving as Raman Reporter for Simultaneous Target Binding and Identification

Technology, Tangible Property / Case number: #25081
Loza Tadesse / Marissa McDonald / Jongwan Lee / Nikiwe Mhlanga
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Mechanisms for Controlled Volume Injection into a Soft Media with Concurrent Pressure Measurement

Technology / Case number: #25109
Nevan Hanumara / Tal Cohen / Alexander Slocum / Brendan Unikewicz / Emily Sologuren / Joseph Morales / Andre Pincot / Sarah Sams
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Analysis, Screening, and Selection for Soluble Protein Function for the Prevention of Infection

Technology / Case number: #25312
Brandon DeKosky
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Molecular Time Capsules Enable Transcriptomic Recording in Living Cells

Technology / Case number: #25337
Gene-Wei Li / Mirae Parker / Jack Rubien / Dylan McCormick
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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An Efficient Bioconjugation Technology for Site-Selective Covalent Modification of Antibodies using an Engineered Affinity Peptide

Technology / Case number: #25358
Bradley Pentelute / Andrei Ioan Loas / Jacob Rodriguez / Heemal Dhanjee / Aurelie Rondon / Katsushi Kitahara
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Multi-Pathway Reporter System that Interrogates Repair of DNA Double-Strand Breaks with Applications for Diagnosis and Therapeutic Treatment of Cancer and Neurodegenerative Diseases

Technology / Case number: #25444
Alex Kruswick / Michael Yaffe
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Machine Learning-guided Whole-Organ Optical Imaging Technique for Non-destructive Identification of Early Pre-Cancer Lesions and Harvesting of Viable Cells from the same for Organoid Culture

Technology / Case number: #25480
Neelkanth Bardhan / Vivek Rastogi / Angela Belcher
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Tuning Chloroplast Transgene Expression from Synthetic Operon

Technology / Case number: #25494
Christopher Voigt / Qiguo Yu
Technology Areas: Agriculture & Food / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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MRR Bioreactor Monitoring

Technology / Case number: #25496
Do Hyun Park / Hans Gaensbauer / Alexander Bevacqua / Jongyoon Han
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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System and Method for Automated Ovarian Follicular Monitoring

Technology / Case number: #19173PJ
Emery Brown / Rose Faghih / Aaron Styer
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science
Impact Areas: Healthy Living
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Locally Delivered Therapeutics and Combinations for Expedited Passage of Urinary Stones

Technology / Case number: #19454J
Michael Cima / Xiang Li / Brian Eisner
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Mammalian Synthetic Biology Approaches for the Precise Control of mAb N-Glycosylation (Pfizer-MIT PTM Track 2 Interim Joint Summary Document)

Technology / Case number: #19972J
Timothy Lu / Ron Weiss / Nevin Summers / Wen Tseng / Leonid Gaydukov / Michelle Chang / Giyoung Jung / Richard Cornell / Jeffrey Marshall / John Scarcelli / Bruno Figueroa
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Catheter for Intracardiac 3D Bioprinting

Technology / Case number: #22338J
Jennifer Lewis / Sebastien Uzel / Ellen Roche / Keegan Mendez / Connor Verheyen / Victor Damptey / Milen Shishkov / Sophie Wang / Markus Horvath / Brett Bouma
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Control Replication and Transcription of Self-Replicating RNA in Responses to Small Molecule TMP

Technology / Case number: #22331H
Ron Weiss / Yingzhong Li / Jan Lonzaric / Parisa Yousefpour / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Centrifugal Microfluidic Platforms for Cell Pairing and Fusion

Technology / Case number: #22275J
MohammadMahdi Aeinhvand / Sergio Martínez-Chapa / Sergio Martinez-Chap / Joel Voldman
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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TRAV-007 (Genome Sequencing) 62/790,799

Technology / Case number: #22143J
Robert Kimmerling / Mark Stevens / Keith Ligon / Scott Manalis
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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