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A Method Leveraging Morphology for Non-Destructive In Situ Mechanical Characterization of Heterogeneous Biological Tissue

Technology / Case number: #23018
Elazer Edelman / Max Olender / David Marlevi / Farhad Rikhtegar Nezami / Bharath Narayanan
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Multi-Input miRNA Sensing with Constitutive ERNs to Regulate Multi-Output Gene Expression in Mammalian Cells

Technology / Case number: #23123
Ron Weiss / Deepak Mishra / Erez Pery / Wenlong Xu / Lei Wang
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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M13 Phage based Gene Therapy Platform (Chapter 4 of Thesis Work)

Technology / Case number: #23296
Uyanga Tsedev / Angela Belcher
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Surgical Cautery Artifact Removal from Electrodermal Activity Data

Technology / Case number: #23525PJ
Emery Brown / Riccardo Barbieri / Sandya Subramanian
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living
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A Fabrication-Free Microfluidic Device for Scalable, High-Volume Bacterial Electroporation

Technology / Case number: #23552
Cullen Buie / Po-Hsun Huang / Sijie Chen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Vikash Chauhan / Robert Langer / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Engineered Alum-binding SARS-CoV-2 Immunogens

Technology / Case number: #23632H
John Love / Neil Dalvie / Sergio Rodriguez / Kristen Rodrigues / Darrell Irvine
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Intracellular Molecular Recording and Memory via Protein Self-Assembly

Technology / Case number: #23746HPM
Edward Boyden / Changyang Linghu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Multifunctional Microelectronics Fibers as Implantable Bioelectronic Interfaces for Central and Peripheral Neuromodulation

Technology / Case number: #23751J
Polina Anikeeva / Tural Khudiyev / Atharva Sahasrabudhe / Laura Rupprecht / Diego Bohórquez
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Activity-based Cell Sorting

Technology / Case number: #23765HJ
Jesse Kirkpatrick / Ava Soleimany / Sangeeta Bhatia
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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DNA-Dye Assembly Based Single-Molecule Fluorescence Lifetime Imaging Probes

Technology / Case number: #23780
Mark Bathe / Stephanie Hart / Xiao Wang / Gabriela Schlau-Cohen / Jiajia Guo
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Lateral Flow Assay Quantifying SARS-Cov-2 Neutralizing Antibody Titer

Technology / Case number: #23869
Hojun Li / Guinevere Connelly
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Method and Apparatus for Inferring Elevated Pulmonary Capillary Wedge Pressures from Single-Lead Electrocardiogram Telemetry Data

Technology, Software / Case number: #23955J
Daphne Schlesinger / Md Ridwanul Alam / Eugene Pomerantsev / Collin Stultz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Activatable Antimicrobial Peptides and Uses Thereof

Technology / Case number: #24024H
Chayanon Ngambenjawong / Sangeeta Bhatia
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Epoxides for Multimodal Detection of Biomolecules by Expansion Microscopy

Technology / Case number: #24137HM
Edward Boyden / Yi Cui / Gaojie Yang
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Intrinsically Stretchable Microelectronic Fibers and Their Assemblies as Multifunctional Bioelectronic Interfaces for Whole Organs

Technology / Case number: #24178
Polina Anikeeva / Atharva Sahasrabudhe / Rajib Mondal
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Universal Redirection of Chimeric Antigen Receptor T Cells Against Solid Tumors via Tumor Cell Membrane-Inserting CAR Ligands

Technology / Case number: #24270H
Angela Zhang / Laura Chen / Alexander Hostetler / Darrell Irvine
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Customized Passive Prosthetic Feet

Technology / Case number: #24341
Amos Winter / Charlotte Folinus
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Tissue-integrating Neural Interfaces

Technology / Case number: #24351
Polina Anikeeva / Anthony Tabet
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Spatial Proteomics using Photocleavable Anchor in Polyelectrolyte Gel

Technology / Case number: #24358HM
Edward Boyden / Camille Mitchell
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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