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Delivery Systems for Anti-Retroviral Drugs

Technology / Case number: #18813J
Robert Langer / Omar Abouzid / Ameya Kirtane / Mousa Jafari / Tyler Grant / Stacy Mo / Angela Diciccio / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Triggerable Shape Memory Gastric Devices for Drug Delivery

Technology / Case number: #17860
Robert Langer / Yida Zhao / Shiyi Zhang / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Enteric Elastomer for Gastrointestinal Devices

Technology / Case number: #17013J
Robert Langer / William Gates / Boris Nikolic / Phillip Eckhoff / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Lowell Wood / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Flexible Polyglycolide Copolymer Barrier Materials

Technology / Case number: #26540
Bradley D. Olsen / Katharina Fransen
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Large-Scale Self-Assembled Nanophotonic Scintillators For X-Ray Imaging

Technology / Case number: #25921
Marin Soljacic / Louis Martin / Simo Pajovic / Charles Roques-Carmes / Juejun Hu
Technology Areas: Chemicals & Materials / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Epigenetic Positive Feedback Loop to Mitigate Transgene Silencing in Mammalian Cells

Technology / Case number: #26152
Sebastian Palacios / Elia Salibi / Domitilla Del Vecchio
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Continuous Flow Lithography

Technology / Case number: #11917
T. Alan Hatton / Patrick Doyle
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Flexible Phase-Transitioning Needles for Shear Stress Reduction

Technology / Case number: #24651J
Giovanni Traverso / Young-Geun Park
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Development of Red to NIR Luminescent Carbodicarbene-Borabenzo[c]anthanthrenium Ions

Technology / Case number: #26386
Robert Gilliard / Bi Youan Tra / Chunlin Deng
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Rational Mutants of Bxb1 Derived from Structural Insights

Technology / Case number: #25675J
Omar Abudayyeh / Teppei Soma / Masahiro Hiraizumi / Christopher Fell / Hiroshi Nishimasu / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Engineered Binding Proteins that Specifically Target Bacteria

Technology / Case number: #22368
Hadley Sikes / Yining Hao / Ki-Joo Sung
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Collapsible Library Design to Enable Characterization of Hyperdiverse Peptide Libraries

Technology / Case number: #26377J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Designing Single Polymer Chain Nanoparticles to Mimic Biomolecular Hydration Frustration

Technology / Case number: #25875
Alfredo Alexander-Katz / Tianyi Jin / Connor Wilson Coley
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Fanzors are RNA-Guided Nucleases Encoded in Eukaryotic Genomes

Technology / Case number: #24942
Omar Abudayyeh / Kaiyi Jiang / Justin Lim / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Robert Langer / Amy Lee / Khanh Tran / Jinbi Tian / Mina Konakovic Lukovic / Ana Jaklenec
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Robert Langer / Vikash Pal Singh Chauhan / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Robert Langer / Linzixuan Rhoda Zhang / Ruiqing Xiao / Ana Jaklenec
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Automated Flow Synthesis of Combinatorial Protein Libraries

Technology / Case number: #26382J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Silicone Valve API Compartment Sealing Barrier

Technology / Case number: #21569QJ
Giovanni Traverso / Brian Jensen / Mikkel Oliver Jespersen / Morten Frederiksen / Alex Abramson
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Robert Langer / Tina Huang / Jooli Han / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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