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1,3,5-triazinane-2,4,6-trione (TNT) Derivatives and Uses Thereof

Technology / Case number: #15446
Robert Langer / Hao Yin / Akinleye Alabi / Joseph Dorkin / Ahmed Eltoukhy / Yizhou Dong / Delai Chen / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Heterocycle-Modified Quinolines for Fluorescence-Based Protein Kinase Sensing

Technology / Case number: #13876
Barbara Imperiali / Juan Gonzalez Vera / Elvedin Lukovic
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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sMutants of Channelrhodopsins with Altered Ion Selectivity

Technology / Case number: #16934TE
Edward Stuart Boyden / Fei Chen / Yongku Cho / Amy Chuong / Nathan Klapoetke
Technology Areas: Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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A Novel Multiplexed Inertial Focusing Microfiltration System for Intra-Operative Blood Salvage Autotransfusion

Technology / Case number: #17212DJE
Jongyoon Han / Kah Ping Andy Tay / Majid Ebrahimi Warkiani / Lidan Wu / Guofeng Guan / Chwee-Teck Lim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Olfactory Receptor-Based Devices

Technology / Case number: #12776TE
Shuguang Zhang / Liselotte Kaiser / Joanke (Johanna) Bikker Graveland / Brian Cook / Andreas Mershin / Manu Prakash / David Kong / Yael Maguire
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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SNAPPLE - Sequencing-Mediated Numerical Analysis of Parallel Proximity Ligation Events

Technology / Case number: #13615B
Andreas Gnirke / Daniel Aird / Erez Lieberman
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Colon Delivery Platform for Constipation Treatment

Technology / Case number: #20570JQ
Robert Langer / Christoph Winfried Johannes Steiger / Joshua Korzenik / Giovanni Traverso
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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A Novel Injectable Thiol-Acrylate Poly(ethylene Glycol) Hydrogel for Sustained Release of Methylprednisolone Sodium Succinate

Technology / Case number: #14439J
Robert Langer / Jonathan Slotkin / Francis Reynolds / Timothy O'Shea / Daniel Siegwart / Christopher Pritchard / Eric Woodard / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / R. Collier / Gizem Akcay / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Self Assembled RSV Nanoparticle Vaccines

Technology / Case number: #16549
Ram Sasisekharan / Aditya Raguram / Vidya Subramanian
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
Tyler Jacks / Leah Schmidt / David Feldser
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

Technology / Case number: #12606B
Moungi G Bawendi / Wenhao Liu / Mark Howarth / Alice Ting
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #12773
Alice Ting / Marta Fernandez Suarez / Yoon-Aa Choi / Hemanta Baruah
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #13846XE
Shuguang Zhang / Yoshiyuki Kumada
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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A Mitochondria Targeting Platinum(IV) Complex with Dual Cell Killing Modes

Technology / Case number: #13271
Stephen J Lippard / Shanta Dhar
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Robert Langer / Stephen Zale / Benjamin Teply / Jianjun Cheng / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Antigenically Intact Hemagglutinin in Circulating Avian and Swine Influenza Viruses and Potential for H3N2 Pandemic

Technology / Case number: #16225
Rahul Raman / Kannan Tharakaraman / Ram Sasisekharan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Darrell J Irvine / Anna Bershteyn / Jae Hyun (James) Moon / Matthias Stephan
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Diminished Proteolytic Shedding of Receptor Tyrosine Kinases Mediates MEK Inhibitor Resistance in Triple-Negative Breast Cancer

Technology / Case number: #16742
Linda Griffith / Madeleine Oudin / Miles Miller / Aaron Meyer / Frank Gertler / Douglas Lauffenburger
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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High Throughput Isolation of Antigen-Specific Antibodies and Cells

Technology / Case number: #16927J
Jongyoon Han / Galit Alter / Aniruddh Sarkar / Han Wei Hou
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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