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Derivation of Enteroendocrine Cells and Insulin Expressing Cells

Technology / Case number: #18445J
Robert Langer / Xiaolei Yin / Jeffrey Michael Karp
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Robert Langer / Shady Farah / Joshua Doloff / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Compositions Systems and Methods for Generating Inner Ear Hair Cells for Treatment of Hearing Loss

Technology / Case number: #17900J
Robert Langer / Nitin Joshi / Xiaolei Yin / Jeffrey Michael Karp
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Implantable Devices and Methods for Evaluation of Active Agents

Technology / Case number: #17867J
No Inventor / John Santini / Oliver Jonas / Jason Fuller / Robert Tepper
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Robert Langer / Hao Yin / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Anti-Zika Virus Antibodies

Technology / Case number: #18525J
Ram Sasisekharan / Subhash Vasudevan / Satoru Watanabe / Kuan Chan / Eng Ooi / Kannan Tharakaraman
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Motorized and Balloon Dynamic Satiety Stimulator

Technology / Case number: #25050JQ
Giovanni Traverso / Neil Jia
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Anantha Chandrakasan / Ian Ballinger / Tom Kerssemakers / Peter Chai / Saurav Maji / SeungHo Lee / Hen Wei Huang / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Robert Langer / Marion Paolini / Jason Andresen / Owen Fenton
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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All-Optical Logic and Quantum-Limited Signal Processing in Large-Scale Optoelectronic Circuits

Technology / Case number: #25208J
Dirk R Englund / Saumil Bandyopadhyay / Ryan Hamerly
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Uncharted Frontiers, Connected World
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Microbial Production of Alpha-Substituted 3-Hydroxy Acids from Glucose

Technology / Case number: #25163
Kristala L Jones Prather / K'yal Bannister
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Attention Buffer

Technology / Case number: #18153QJ
Bryan Reimer / Bobbie Seppelt / Linda Angell / Joonbum Lee / Bruce L Mehler / Joseph Coughlin
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Uncharted Frontiers
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Matching Individual Using Genetic Data for Risk Prediction

Technology / Case number: #19308PQ
Manolis Kellis / Sandeep Nuckchady / Dianbo Liu / Anne Kim / Lauren Huang / Zhizhuo Zhang
Technology Areas: Computer Science
Impact Areas: Healthy Living
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Decoding via Guessing Noise

Technology / Case number: #20169J
Muriel Medard / Kenneth Duffy / Jiange Li
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Uncharted Frontiers
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Daniel Anderson / Idris Raji / Jacob Witten
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Thermo-Responsive, Inflammation-Targeting (TRIT) Hydrogel Formulations for Local Drug Delivery in Intestinal Inflammation

Technology / Case number: #19181J
Robert Langer / Joshua Korzenik / Ashok Kakkar / Sufeng Zhang / Giovanni Traverso
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Chia-fu Chang / Christina Woo / Sebastian Pomplun / Catherine Henry / Jasmin Kruell / Brice Curtin
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Small Molecule Inhibitors of Interleukin-4

Technology / Case number: #22186J
Angela Koehler / Sean Quinnell / Daniel Sheehy / Luke Ceo / Kelly Tan / Stephen Nestor / Becky Leifer / Shelby Doyle / Arturo Vegas
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Tough Hydrogel Pills Inflating 100 Times in Volume Within 10 Min

Technology / Case number: #20059
Xuanhe Zhao / Xinyue Liu / German Parada Hernandez / Hyunwoo Yuk / Shaoting Lin
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Gastric Residence Electronics

Technology / Case number: #20092J
Robert Langer / Yong Lin Kong / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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