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Novel Chimeric Antigen Receptor Signaling Domains Derived via Activity-based Directed Evolution

Technology / Case number: #21116
Michael Birnbaum / Taeyoon Kyung
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Rhinometric Sensing and Gas Detection

Technology / Case number: #21117
Ian Hunter / Nickolas Demas
Technology Areas: Sensing & Imaging
Impact Areas: Climate Stabilization
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Arterial Wall Characterization in Optical Coherence Tomography Imaging

Technology / Case number: #21209
Elazer R Edelman / Lambros Anthanasiou / Max Olender
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Optimization of Circular Single Stranded DNA using M13 Phage

Technology / Case number: #21211
Angela Belcher / Tae-Gon Cha / Uyanga Tsedev / Christopher Voigt
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Emboli Detection Methods to Identify Stroke Mechanism or Stroke Risk in Susceptible Adults and Children

Technology, Software / Case number: #21233J
Thomas Heldt / Barry Kussman / Kerri LaRovere / Syed Imaduddin
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Exhalation Emission Simulator

Technology / Case number: #22626
Lydia Bourouiba / Yongji Wang / Rishabh Datta
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Dynamic Control of a Fiber Manufacturing Process using Deep Reinforcement Learning

Technology / Case number: #22652
Brian Anthony / Sangwoon Kim / Donghyun Kim
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Industrial Engineering & Automation
Impact Areas: Connected World
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Non-Invasive Staging of Liver Steatosis and Fibrosis via Single-Sided Magnetic Resonance Sensors

Technology / Case number: #22685
Michael Cima / Christopher Frangieh / Ashvin Bashyam
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Compositions of Polypeptides for Subunit Vaccines for SARS-CoV-2

Technology / Case number: #22703
J. Christopher Love / Sergio Rodriguez / Neil Dalvie
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Method to Simulate Metrics of Vascular Function from Clinical Data

Technology / Case number: #22712
Elazer R Edelman / Michael Murphy / Jonathan Brown
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Perfusable Host Microfluidic Endothelial Networks for Spheroid and Organoid Co-culture and Immune Cell Infiltration Studies

Technology / Case number: #22749
Roger Kamm / Sharon Lee / Huu Tuan Nguyen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Fusion Capsid Therapy for COVID-19 and Applies to Other Viruses: Universal "Dominant" Antiviral to Prevent Virus Evolution and Future Pandemics (DNA/RNA/Protein)

Technology, Tangible Property / Case number: #22801MH
Robert Langer / Bowen Li / Yong Qian / Alexi Choueiri / Edward Stuart Boyden / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Fenestration Alignment Program

Technology / Case number: #22841J
Ellen Roche / Marc Schermerhorn / Patric Liang / Tom Dillon
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Crosslinking Comonomers for High Performance Degradable Thermosets

Technology / Case number: #22863
Jeremiah A. Johnson / Keith Husted / Peyton Shieh
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
License

A Tunable Phosphorylation-based Feedback Controller of Mammalian Gene Expression

Technology / Case number: #22932
Ron Weiss / Yili Qian / Domitilla Del Vecchio / Ross Jones
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Identification of Genes and Mutations that Underlie Adaptation of Gut Microbes to Denovo Degradation of Oxalate

Technology / Case number: #23007
Jeff Gore / Avihu Yona
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Molecular Memory Retrieval by Position-based Addressing

Technology / Case number: #21829
Tyson Shepherd
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Connected World
License

Accurate Genome Editing

Technology / Case number: #21848
Timothy K Lu / Shota Nakade
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Crosslinked Hydrocarbon Fragments and Methods of Use Thereof

Technology / Case number: #21909
Jeremiah A. Johnson / Keith Husted / Peyton Shieh / Wenxu Zhang
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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Cheaper, Environmentally Friendly, and Sustainable Biofuel Production through Yeast System

Technology / Case number: #21974
Angela Belcher / Shalmalee Pandit
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Sustainable Future
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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