Mark Bathe

Professor

Department
Department of Biological Engineering
Technology Areas
Biotechnology: DNA & RNA Editing, Biomedical Devices & Systems, Sensors & Monitoring, Synthetic Biology, Biomanufacturing / Drug Discovery and Research Tools: Genomics & Proteomics, Cell Interrogation / Therapeutics: Small Molecules, Nucleic Acids, Proteins & Antibodies, Vaccines / Chemicals & Materials: Nanotechnology & Nanomaterials, Catalysis & Synthesis, Polymers / Diagnostics: Imaging Agents, Assays / Electronics & Photonics: Photonics, Quantum Technology, Semiconductors / Computer Science: Bioinformatics / Artificial Intelligence (AI) and Machine Learning (ML)

Computational and experimental engineering of DNA and other biomolecules to enable advanced imaging, diagnostic, and therapeutic applications in synthetic biology.

Background and Experience

Dr. Bathe is a Professor in the Department of Biological Engineering at MIT, Director of the MIT New Engineering Education Transformation, Member of the Harvard Medical School Initiative for RNA Medicine, and Associate Member of the Broad Institute of MIT & Harvard. He obtained his Doctoral Degree at MIT working in the Departments of Mechanical, Chemical, and Biological Engineering before moving to the University of Munich as an Alexander von Humboldt Fellow to carry out his postdoctoral research in Biological Physics. He returned to MIT in 2009 to join the faculty in the Department of Biological Engineering, where he runs an interdisciplinary research group focused on the targeted delivery of therapeutic nucleic acids and vaccines, phenotypic profiling of neuronal circuits involved in psychiatric disease, and engineering nucleic acid materials for highly parallel molecular computing and massive data storage.

Technologies

Structured DNA Nanoparticle Platform for Protein- and Peptide-based Vaccines

Technology / Case number: #20929H
Darrell J Irvine / Benjamin Read / Eike-Christian Wamhoff / Tyson Moyer / Rebecca Du / Remi Veneziano / Mark Bathe
Technology Areas: Chemicals & Materials / Therapeutics
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