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Machine Learning for the Design of Cancer Vaccine Adjuvants

Technology / Case number: #21680J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Reker / Robert Langer / Lewis Scott Jones / Hyunjoon Kim / Netra Rajesh
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Anti-Zika Virus Antibodies

Technology / Case number: #18525J
Kannan Tharakaraman / Eng Ooi / Kuan Chan / Satoru Watanabe / Subhash Vasudevan / Ram Sasisekharan
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Pooled Screening Identifies Genomic Features (Biomarkers) Modulating Nanoparticle-Cell Interactions

Technology / Case number: #22785J
Angela Koehler / Natalie Boehnke / Joelle Straehla / Paula Hammond
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Dysferlinopathy Compounds

Technology, Tangible Property / Case number: #22496
Mohan Viswanathan / Eric Williams / Kana Tominaga / Naoomi Tominaga / Leonard Guarente
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Synthesis of Covalent Protein Dimers that can Inhibit MYC-Driven Transcription

Technology / Case number: #23305WJ
Bradley Pentelute / Isaac Klein / Carly Schissel / Sebastian Pomplun / Andrei Ioan Loas / Jacob Rodriguez / Muhammad Jbara / Ann Boija / Susana Hawken / Charles Li / Stephen Buchwald
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Synthetic Gene Circuits and Parts in Bacteroides

Technology / Case number: #17815
Timothy Lu / Mark Mimee / Christopher Voigt / Alex Tucker
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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A Platform for Continuous Directed Evolution in Human Cells

Technology / Case number: #19909
Matthew Shoulders / Louis Papa / Christopher Moore / Chet Berman / Samuel Hendel
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Compositions and Methods to Increase Muscular Strength Without Exercise

Technology / Case number: #19768
Roger Kamm / Vivek Sivathanu
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Potent Agelastatin Derivatives as Modulators for Cancer Invasion and Metastasis

Technology / Case number: #19505J
Mohammad Movassaghi / Rachel Buchsbaum / Alyssa Antropow / Kun Xu
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Diazene Directed Modular Synthesis of Oligocyclotryptamines

Technology / Case number: #18747
Mohammad Movassaghi / Petra Lindovska
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
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Enhancing tumor immunogenicity with Hsp90 inhibition

Technology / Case number: #20303WHJ
Luke Whitesell / Alexander Jaeger / Sandro Santagata / Tyler Jacks / Susan Lindquist
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Layer-by-Layer Nanoparticles for Cytokine Therapy in Cancer Treatment

Technology / Case number: #20027H
Erik Dreaden / Mariane Melo / Antonio Barberio / Santiago Correa Echavarria / Talar Tokatlian / Darrell Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Methods and Compositions for Increasing Sensitivity of Cancer Cells to Glutaminase Inhibitors and Applications to Cancer Therapy

Technology / Case number: #19305
Matthew Vander Heiden / Dan Gui / Alexander Muir / Laura Danai
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Methods for Gene Delivery with Papillomaviruses

Technology / Case number: #21704
Omar Abudayyeh / Jonathan Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Structured DNA Nanoparticle Platform for Protein- and Peptide-based Vaccines

Technology / Case number: #20929H
Mark Bathe / Remi Veneziano / Rebecca Du / Tyson Moyer / Eike-Christian Wamhoff / Benjamin Read / Darrell Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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