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Diminished Proteolytic Shedding of Receptor Tyrosine Kinases Mediates MEK Inhibitor Resistance in Triple-Negative Breast Cancer

Technology / Case number: #16742
Linda Griffith / Madeleine Oudin / Miles Miller / Aaron Meyer / Frank Gertler / Douglas Lauffenburger
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Development of New Zwitterionic Chemistry for Ultralow Biofouling of Commercial RO Membranes

Technology / Case number: #16765J
Karen Gleason / Hafiz Zahid Shafi / Zafarullah Khan / Rong Yang
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future
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PolyMOFs: Hybrid Materials With Combined Gel and MOF Properties Via Metal-Ligand Coordination and Self-Assembly

Technology / Case number: #16872
Jeremiah A. Johnson / Ken Kawamoto / Scott Grindy / Niels Holten-Andersen / Aleksandr Zhukhovitskiy
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Connected World
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Superelastic Shape Memory Ceramic Particles and the Preparation Therefore

Technology / Case number: #16922J
Christopher Schuh / Hang Yu / Chee Lip Gan / Zehui Du
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Connected World
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High Throughput Isolation of Antigen-Specific Antibodies and Cells

Technology / Case number: #16927J
Jongyoon Han / Galit Alter / Aniruddh Sarkar / Han Wei Hou
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Salmochelin-Antibiotic Conjugates for Targeting Gram-Negative Pathogens

Technology / Case number: #16939
Elizabeth M. Nolan / Phoom Chairatana / Tengfei Zheng
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Siderophore-Based Immunization Against Gram-Negative Bacteria

Technology / Case number: #16976J
Elizabeth M. Nolan / Araceli Perez-Lopez / Martina Corsi / Manuela Raffatellu / Phoom Chairatana
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Novel Acidic Reagents for Enhanced Detection of Inorganic Oxidizers

Technology / Case number: #16985L
Rod Kunz / Alla Ostrinskaya / Jude Kelley / Richard Kingsborough
Technology Areas: Chemicals & Materials / Sensing & Imaging
Impact Areas: Connected World
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Continuous Fabrication Platform for Highly Aligned Polymer Films

Technology, Tangible Property / Case number: #17065
Gang Chen / Yanfei Xu / James Loomis / Xiaopeng Huang / Hadi Ghasemi / Jonathan Tong / Jianjian Wang
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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One-Step Protein Analysis Using Slanted Nanofilter Array

Technology / Case number: #17391
Jongyoon Han / Sung Ko
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Hindering Oxygen Mobility in Lithium-Excess Disordered Rocksalt Cathodes by Polyanionization Solid Solution

Technology / Case number: #24890
Ju Li / Yimeng Huang / Yanhao Dong
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Continuous Catalytic Synthesis of alpha-methylene-delta-valerolactone Using Solid Bases

Technology / Case number: #25282
Yuriy Roman / Lucas Baston / Alexander Khechfe
Technology Areas: Chemicals & Materials
Impact Areas: Connected World
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Branched Chain Fatty Acids Have Immune-Modulatory Effects

Technology / Case number: #25569P
Li-Huei Tsai / Lorenzo Bozzelli
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Micronutrient-Stabilizing Materials

Technology / Case number: #25722
Robert Langer / Xin Yang / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Bright and Fast Emission from Robust Supramolecular J-aggregate Nanostructures through Silica-Encapsulation

Technology / Case number: #25820
Moungi G Bawendi / Ulugbek Barotov / Dimuthu Thanippuli Arachchi
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Connected World
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Methane Absorbing Polymers for use in Methane Concentration and Separations

Technology / Case number: #26018
Timothy Manning Swager / Haosheng Feng
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Connected World
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MMAF-Conjugated Layer-by-Layer Nanoparticles for Local Glioblastoma Treatment

Technology / Case number: #25705
Paula Hammond / Andrew Pickering / Nicholas Lamson / Michael Marand
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Methodology to Deconvolve Metabolic Heterogeneity

Technology / Case number: #25787J
Yunping Qiu / Alison Ringel / Lillian Delacruz / Irwin Kurland
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Machine-Learning Optimized Proteins and Enzymes

Technology / Case number: #26015J
Omar Abudayyeh / Zhaoqing Yan / Matteo Di Bernardo / Kaiyi Jiang / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Fluorine-Free Crosslinked Siloxane Surface Coatings

Technology / Case number: #26049
Farnaz Niroui / Eduard Bobylev / Peter Satterthwaite / Jeremiah A. Johnson
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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