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Recombinase-Based Genetic Diversification Schemes

Technology / Case number: #18173
Timothy Lu / Sara Da Luz Areosa Cleto
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Multilayer Genetic Safety Kill Circuits Based on Single Cas9 Protein and Multiple Engineered gRNA in Mammalian Cells

Technology / Case number: #18163
Ron Weiss / Mohammad Reza Ebrahimkhani / Samira Kiani
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Method to Treat Amblyopia

Technology / Case number: #18125PH
Mark Bear / Jeffrey Gavornik / Kevin Duffy / Donald Mitchell / Ming-fai Fong / Arnold Heynen
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method to Distinguish and Analyze White Blood Cells in the Presence of Red Blood Cells

Technology / Case number: #18889
Shivang Dave / Jason Tucker-Schwartz
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Electromechanical Lysis of Bacterial Pathogens using Ion Concentration Polarization

Technology / Case number: #19035
Minseok Kim / Jongyoon Han
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Efficient Smith-Purcell Radiation Sources and Enhancement Methods

Technology / Case number: #19456
Steven Kooi / Ido Efraim Kaminer / Nicholas Rivera / Yi Yang / Tena Dubcek / Aviram Massuda / Charles Roques-Carmes / Yujia Yang / John Joannopoulos / Marin Soljacic / Karl Berggren
Technology Areas: Electronics & Photonics / Environmental Engineering / Sensing & Imaging
Impact Areas: Advanced Materials
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Atherofluidics-on-Chip

Technology / Case number: #18096
Sarvesh Varma / Joel Voldman
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Compositions and Methods for Treating and Preventing Obesity

Technology / Case number: #18085J
Manolis Kellis / Melina Claussnitzer / Jan Korbel
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Jointly Learning Audio and Visual Patterns with Deep Neural Networks

Technology / Case number: #18815
David Harwath / James Glass
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Connected World
License

Multiplexed Specific Metalloprotease Activity Measurements

Technology / Case number: #19425DE
Miles Miller / Caroline Chopko Ahrens / Christi Cook / Steven Tannenbaum / Ravindra Kodihalli / Evan Chiswick / Linda Griffith / Douglas Lauffenburger
Technology Areas: Biomaterials & Bioelectronics / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Open-Ended, Dicer-Cleavable Concatemeric siRNA Generated by Rolling Circle Transcription

Technology / Case number: #18076
Connie Wu / Kevin Shopsowitz / Paula Hammond
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Development of Multi-Specific Antibody-Serum Albumin Fusion Proteins Targeting Multiple Human and Murine CXC (ELR+) Chemokines

Technology / Case number: #19355JQ
Alessandro Angelini / Andrew Luster / Karl Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Engineered Yeast As a Method for Bioremediation

Technology / Case number: #18804
George Sun / Angela Belcher
Technology Areas: Biotechnology / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Delivery of Preassembled Double-Stranded Short Interference RNA-Argonaute Protein Complexes for Enhanced RNAi-Based Therapeutics

Technology / Case number: #19340
Jiahe Li / Yanpu He / Wade Wang / Paula Hammond
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
License

METRAN - Software for 13C-metabolic Flux Analysis

Software / Case number: #12397
Technology Areas: Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Connected World
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Structured DNA Conjugates

Technology / Case number: #18588
Mark Bathe / Sakul Ratanalert / Remi Veneziano / Tyson Shepherd / Hyungmin Jun
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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N/ASynergistic Tumor Treatment with IL-2, an Integrin-Binding-FC Fusion Protein, and a Cancer Vaccine

Technology / Case number: #18598HJ
Byron Kwan / Cary Opel / Kelly Moynihan / Darrell Irvine / Jennifer Cochran / Karl Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
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Printable Programmable Viscoelastic Materials

Technology / Case number: #18624
Daniela Rus / Robert MacCurdy / Jeffrey Lipton
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Advanced Materials
License

Eye Tracking as a Language Proficiency Test

Technology / Case number: #19689
Yevgeni Berzak / Roger Levy / Boris Katz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Sensing & Imaging
Impact Areas: Connected World
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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