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Systems and Assays for Identifying PU.1 Inhibitors

Technology / Case number: #21734P
Li-Huei Tsai / William Ralvenius / Alison Mungenast
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Circular, Strained Zymogen

Technology / Case number: #21110J
Ronald Raines / Ian Windsor
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Acute Sensitivity Testing of Cancer Samples Using Functional Cell Mass and Imaging Biomarkers or Drug Response

Technology / Case number: #21001J
Selim Olcum / Robert Kimmerling / Nicholas Calistri / Mark Stevens / Keith Ligon / Seth Malinowski / Mehdi Touat / Mark Murakami / David Weinstock / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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1. Methods for in Vitro Evolution of Constructs Derived from Viruses. 2. Five Mutations Derived from the in Vitro Evolution. 3. Seventeen constructs from the five mutations.

Technology / Case number: #20395H
Ron Weiss / Yingzhong Li / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Anti-Human KLRB1 Monoclonal Antibodies and Uses Thereof

Technology / Case number: #21645J
Kai Wucherpfennig / Byong Ha Kang / Nathan Mathewson / Karl Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Single-Cell Density as A Biomarker for Drug Sensitivity

Technology / Case number: #23741J
Keith Ligon / Richard Wu / Teemu Miettinen / Sarah Ishamuddin / Kin-Hoe Chow / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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High-Throughput and High-Precision Measurement of Single-Cell Density

Technology / Case number: #23740
Richard Wu / Teemu Miettinen / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Split Intein-based Selection for Modified Peptide Binders to SARS-CoV-2 Spike Protein

Technology / Case number: #22502
Christopher Voigt / Emerson Glassey / Andrew King
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Medical Recordkeeping Microneedles

Technology / Case number: #24923
Ana Jaklenec / Robert Langer / Maria Kanelli / Jooli Han / Yang Liu / Frederic Durand (he/him/his)
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods for Machine-Learning Guided Protein Design

Technology / Case number: #25084
Omar Abudayyeh / Jonathan Gootenberg / Kaiyi Jiang / Matteo Di Bernardo
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Redox-Electrodes for Electrochemically-Controlled Bio-Macromolecule Interaction: Bio-Separations, Heterogeneous Enzyme Immobilization, Protein Purification and Sensing, Among Others

Technology / Case number: #18540
Trevor Hatton / Xiao Su
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Method for Foam Mitigation Using Hydrophobic Surfaces

Technology / Case number: #19845
Leonid Rapoport / Kripa Varanasi
Technology Areas: Agriculture & Food / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Redox-Functionalized Electrodes for Selective Electrochemical Separation, Molecular Recognition and Energy Storage as Well as Other Related Applications

Technology / Case number: #18239
Trevor Hatton / Xiao Su / Demetra Achilleos
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Multi-Stage Adsorption-Based Atmospheric Water Harvesting

Technology / Case number: #21788
Evelyn Wang / Alina LaPotin / Yang Zhong
Technology Areas: Energy & Distribution / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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TRAV-005 (Needles) 62/795,857

Technology / Case number: #22144J
Selim Olcum / Robert Kimmerling / David Weinstock / Scott Manalis
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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All-Optical Holographic Implementation of Constant-Depth Quantum Circuits

Technology / Case number: #21655
Dirk Englund / Donggyu Kim
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Advanced Materials
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Machine Learning for Accelerated IBFD Tuning

Technology / Case number: #22007L
Kenneth Kolodziej / Bradley Perry / Aidan Cookson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Connected World, Advanced Materials
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Certified Control

Technology / Case number: #21653
Soonho Kong / Jonathan DeCastro / Dimitrios Koutentakis / FengPing Angela Leong / Mike Wang / Nikos Gonzalez / Xin Zhang / Daniel Jackson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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Task Specific Chelating Ionic Liquids for Removal of Metal Ions from Aqueous Solution via Liquid/Liquid Extraction and Electrochemistry

Technology / Case number: #20131
Trevor Hatton / Paul Brown / Sahag Voskian
Technology Areas: Environmental Engineering
Impact Areas: Sustainable Future
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Rapid Droplet-Based Systems for Antibody Drug Discovery

Technology / Case number: #23890J
Brandon DeKosky / Matias Gutierrez Gonzalez / Cheng-yu Chung / Ahmed Fahad / Nicoleen Boyle / Shuyan Jin
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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