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Structure and Engineering of the Type III-E CRISPR-Cas7-11 Effector Complex

Technology / Case number: #23945J
Omar Abudayyeh / Jonathan Gootenberg / Wenyuan Zhou / Hiroshi Nishimasu / Kazuki Kato / Cian Schmitt-Ulms
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Polymeric Solid-State MRI Contrast Agents for pH Quantification

Technology / Case number: #18380
Michael Cima / Gregory Ekchian
Technology Areas: Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Transcriptional Sensor for Bile Acids in Bacteroides Thetaiotaomicron

Technology / Case number: #18573
Christopher Voigt / Mao Taketani
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Microbial System for Biosynthesis of Natural and Engineered Products Coupled to in Situ Extraction in Supercritical CO2

Technology / Case number: #18721
Kristala Prather / Janelle Thompson / Kyle Peet / Adam Freedman / Jason Boock / Michael Timko
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future
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An RNA Sequencing Method for Absolute Quantification of RNA Molecules

Technology / Case number: #20363
Peter Dedon / Michael DeMott / Bo Cao / Jennifer Hu
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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rcSso7d.SA Oligomer-PNIPAM Conjugates

Technology / Case number: #20442
Bradley Olsen / Hadley Sikes / Eric Miller / Justin Paloni
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Optical Methods Level Sensor for Use in a Bioreactor

Technology / Case number: #19143
John Love / Richard Braatz / Craig Mascarenhas / Amos Lu
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Novel Small Molecule Modulators of Myb-Mediated Transcription with Potential Use for Cancer Therapy

Technology / Case number: #22044
Angela Koehler / Becky Leifer / Florian Kabinger / Brice Curtin / Jasmin Kruell
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Native Context Mapping of the Regulatory Genome

Technology / Case number: #18012JQ
Nisha Rajagopal / Richard Sherwood / David Gifford
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Method and Apparatus for Imaging Unsectioned Tissue Specimens

Technology / Case number: #18516
Michael Giacomelli / Tadayuki Yoshitake / Lucas Cahill / James Fujimoto
Technology Areas: Diagnostics / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Continuous Freeze-Drying of Pharmaceuticals and Biopharmaceuticals in Unit Doses

Technology / Case number: #19494J
Roberto Pisano / Capozzi Carlo / Bernhardt Trout
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method to Distinguish and Analyze White Blood Cells in the Presence of Red Blood Cells

Technology / Case number: #18889
Shivang Dave / Jason Tucker-Schwartz
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Biomedical Imaging and Optical Stimulation Device

Technology / Case number: #18022
Juejun Hu / Tian Gu / Qi Qin
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Diazene Directed Modular Synthesis of Oligocyclotryptamines

Technology / Case number: #18747
Mohammad Movassaghi / Petra Lindovska
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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New Methods to Assess Fluid Distribution in Muscle Tissue via Single Sided Magnetic Resonance Sensors

Technology / Case number: #21335
Michael Cima / Ashvin Bashyam / Christopher Frangieh
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Intracellular Calcium Sensors for MRI

Technology / Case number: #20143
Ali Barandov / Benjamin Bartelle / Alan Jasanoff
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Nitroxide-Based Macromolecular Contrast Agents with Unprecedented Transverse Relaxivity and Stability for Magnetic Resonance Imaging of Tumors

Technology / Case number: #19540J
Jeremiah Johnson / Hung Nguyen / Andrzej Rajca
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Removal of Ruthenium-Initiator from Brush-Arm Star Polymers (BASPs) via Core-to-Surface Ring-Opening Methathesis Polymerization (ROMP)

Technology / Case number: #19525
Jeremiah Johnson / Matthew Golder
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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GLYCAN-BINDING PROTEINS AND RELATED COMPOSITIONS AND METHODS

Technology / Case number: #21107
Cristina Cella / Elizabeth Ward / Barbara Imperiali
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Bfl-1

Technology / Case number: #18607
Amy Keating / Justin Jenson
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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