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Method to Simulate Metrics of Vascular Function from Clinical Data

Technology / Case number: #22712
Elazer Edelman / Jonathan Brown / Michael Murphy
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Perfusable Host Microfluidic Endothelial Networks for Spheroid and Organoid Co-culture and Immune Cell Infiltration Studies

Technology / Case number: #22749
Roger Kamm / Huu Tuan Nguyen / Sharon Lee
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Closed-Loop System for Blood Pressure Control

Technology / Case number: #22797
Emery Brown / Taylor Baum
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living
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Fenestration Alignment Program

Technology / Case number: #22841J
Ellen Roche / Tom Dillon / Patric Liang / Marc Schermerhorn
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Non-Invasive Tactile Stimulation for Improving Motor Function

Technology / Case number: #22928P
Li-Huei Tsai / Ho-Jun Suk / Guojie Xu / Arit Banerjee
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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A Tunable Phosphorylation-based Feedback Controller of Mammalian Gene Expression

Technology / Case number: #22932
Ron Weiss / Ross Jones / Domitilla Del Vecchio / Yili Qian
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Fluidic Platform for Perfusable Vascularized Tumor Spheroids and Organoids

Technology / Case number: #22942
Roger Kamm / Zhengpeng Wan / Shun Zhang
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Identification of Genes and Mutations that Underlie Adaptation of Gut Microbes to Denovo Degradation of Oxalate

Technology / Case number: #23007
Jeff Gore / Avihu Yona
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Method Leveraging Morphology for Non-Destructive In Situ Mechanical Characterization of Heterogeneous Biological Tissue

Technology / Case number: #23018
Elazer Edelman / Max Olender / David Marlevi / Farhad Rikhtegar Nezami / Bharath Narayanan
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Multi-Input miRNA Sensing with Constitutive ERNs to Regulate Multi-Output Gene Expression in Mammalian Cells

Technology / Case number: #23123
Ron Weiss / Deepak Mishra / Erez Pery / Wenlong Xu / Lei Wang
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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M13 Phage based Gene Therapy Platform (Chapter 4 of Thesis Work)

Technology / Case number: #23296
Uyanga Tsedev / Angela Belcher
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Surgical Cautery Artifact Removal from Electrodermal Activity Data

Technology / Case number: #23525PJ
Emery Brown / Riccardo Barbieri / Sandya Subramanian
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living
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A Fabrication-Free Microfluidic Device for Scalable, High-Volume Bacterial Electroporation

Technology / Case number: #23552
Cullen Buie / Po-Hsun Huang / Sijie Chen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Vikash Chauhan / Robert Langer / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Engineered Alum-binding SARS-CoV-2 Immunogens

Technology / Case number: #23632H
John Love / Neil Dalvie / Sergio Rodriguez / Kristen Rodrigues / Darrell Irvine
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Intracellular Molecular Recording and Memory via Protein Self-Assembly

Technology / Case number: #23746HPM
Edward Boyden / Changyang Linghu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Multifunctional Microelectronics Fibers as Implantable Bioelectronic Interfaces for Central and Peripheral Neuromodulation

Technology / Case number: #23751J
Polina Anikeeva / Tural Khudiyev / Atharva Sahasrabudhe / Laura Rupprecht / Diego Bohórquez
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Activity-based Cell Sorting

Technology / Case number: #23765HJ
Jesse Kirkpatrick / Ava Soleimany / Sangeeta Bhatia
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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DNA-Dye Assembly Based Single-Molecule Fluorescence Lifetime Imaging Probes

Technology / Case number: #23780
Mark Bathe / Stephanie Hart / Xiao Wang / Gabriela Schlau-Cohen / Jiajia Guo
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Lateral Flow Assay Quantifying SARS-Cov-2 Neutralizing Antibody Titer

Technology / Case number: #23869
Hojun Li / Guinevere Connelly
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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