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Self Actuating Systems for Retention and Electrical Stimulation in the Gastrointestinal Tract

Technology / Case number: #20292JQ
Robert Langer / David Dellal / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Self-Actuating Needle/Biopsy Punch

Technology / Case number: #19808J
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Solid Formulations with Ultra-High Drug Loading

Technology / Case number: #19446J
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Multi-Pronged Self-Orienting Millimeter-Scale Actuator for Drug Delivery

Technology / Case number: #21169JQ
Robert Langer / Jacob Wainer / Michael Williams / Alex Abramson / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Self-Righting Systems for Tissue Wall Localization

Technology / Case number: #19012JQ
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Daniel Minahan / Taylor Bensel / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Injectable, Thermogelling, Prolonged-Release Hydrogel Formulations for CPG-ODNs

Technology / Case number: #26051J
Robert Langer / Stephen Linderman / Eric Wehrenberg-Klee / Jan-Georg Rosenboom / Avik Som / Ameya Kirtane / Giovanni Traverso
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Wearable Bio-adhesive Metal Detector Array (BioMDA) for Spinal Implants

Technology / Case number: #26075J
Giovanni Traverso / Xinge Yu / Jian Li / Ganesh Shankar / Kewang Nan
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

Technology / Case number: #25731J
Daniel Anderson / Christopher Garris / Riddha Das / Kaelan Reed / Akash Gupta / Ralph Weissleder
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Flexible Phase-Transitioning Needles for Shear Stress Reduction

Technology / Case number: #24651J
Giovanni Traverso / Young-Geun Park
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Self-Righting Systems, Methods, and Related Components

Technology / Case number: #20706JQ
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Enteric Elastomer for Gastrointestinal Devices

Technology / Case number: #17013J
Robert Langer / William Gates / Boris Nikolic / Phillip Eckhoff / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Lowell Wood / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Method for Controlling mRNA-Loaded Lipid Nanoparticles through Post-Injection and Buffer Control

Technology / Case number: #26460
Allan S. Myerson / Cedric Devos / Aniket Pradip Udepurkar / Peter Sagmeister / Richard D Braatz
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Immunotherapeutic Approaches Directed at MZB1 for Plasma Cell and B Cell Malignancies

Technology / Case number: #26513J
Jianzhu Chen / Mariateresa Fulciniti / Mehmet Samur / Elena Maroto Martin / Yingjie Zhao / Nikola Ivica / Mikhil Munshi
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Drug Delivery Devices For Gastrointestinal Retention

Technology / Case number: #17002J
Robert Langer / Jiaqi Lin / Stacy Mo / Angela Diciccio / William Gates / Boris Nikolic / Phillip Eckhoff / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Lowell Wood / Giovanni Traverso
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Flexible Polyglycolide Copolymer Barrier Materials

Technology / Case number: #26540
Bradley D. Olsen / Katharina Fransen
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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A REtrievable IntravaSCUlar Implant SystEm (RESCUE) for Cell Therapy

Technology / Case number: #26283J
Robert Langer / Jong Seung Lee / Matt Murphy / SeungHo Lee / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Delivery Systems for Anti-Retroviral Drugs

Technology / Case number: #18813J
Robert Langer / Omar Abouzid / Ameya Kirtane / Mousa Jafari / Tyler Grant / Stacy Mo / Angela Diciccio / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Strategy to Improve Genotoxic Chemotherapy using the Rev1 C-Terminal Domain

Technology / Case number: #26149
Graham Walker / Charley Gruber / Kevin Bian / Michael Hemann
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Using Gamma Sensory Entriainment to Rescue Brain Development Defects in Down Syndrome

Technology / Case number: #26448P
Li-Huei Tsai / Md Rezaul Islam / Dong Shin Park
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Microfabricated Wireless Biomedical Devices

Technology / Case number: #26315TE
Deblina Sarkar / Hao-Tung Yang / Benoit Desbiolles / Yubin Cai / Baju Chiyezhath Joy
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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