Available Technologies

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Cell-Surface Anchored Cytokine Therapy

Technology, Tangible Property / Case number: #25245H
Luciano Santollani / Darrell Irvine / Karl Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Engineered Synthetic IRES with Improved and Robust Translation in Circular RNA

Technology / Case number: #25300YJ
James Collins / Katherine Ilia / Shiva Razavi / Kehan Zhang / Xiaoyu Chen / Makoto Lalwani / Yu Li / Nayoung Kim
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Combinations of Anesthetics as Therapies for Treatment-Resistant Depression

Technology / Case number: #25342P
Emery Brown / Sirma Orguc / Ohyoon Kwon / Bryan Tseng / Macauley Breault / Gloria Kang
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Reconstituted Lipoprotein Particles to Rescue Lipid Defects in the Alzheimer's Brain

Technology / Case number: #25445P
Li-Huei Tsai / Rebecca Pinals
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method of Enhanced Clearance of Uremic Toxins in Hemodialysis using Nanoporous Membranes

Technology / Case number: #21853
Rohit Karnik / Aaron Persad / Chun Man Chow / Chi Cheng
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
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Optimized Alum-Anchored HIV Env Immunogens

Technology / Case number: #24972HJ
Kristen Rodrigues / Christopher Cottrell / Jon Steichen / William Schief / Darrell Irvine
Technology Areas: Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Selective Valorization of Biomass Sugars

Technology / Case number: #21846
Alison Wendlandt / Yong Wang / Hayden Carder
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
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Biodegradable Lipids and Formulations for Intramuscular, In Vitro, and Ex Vivo Transfection of mRNA

Technology / Case number: #23969J
Arnab Rudra / Akash Gupta / Kaelan Reed / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
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A Diagnostic and Treatment Prediction Toolkit for Bipolar Disorder based on Polymorphisms in CPG2 Regulatory Domains

Technology / Case number: #23591P
Baovi Vo / Elly Nedivi
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Functionalization of MiniHA with Lauric Acid

Technology / Case number: #20135
Bradley Olsen / Allie Obermeyer / Sieun Kim / Lavinia Popescu / Yun Jung Yang
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Thermogelling Nanoemulsions for Pharmaceutical Manufacturing

Technology / Case number: #22768
Patrick Doyle / Liang-Hsun Chen
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Dielectric Films for the Control of Cell Adhesion

Technology / Case number: #23881
Victor Leon / Baptiste Blanc / Sophia Sonnert / Kripa Varanasi
Technology Areas: Biotechnology / Drug Discovery and Research Tools
License

Thermal Imaging-based State Estimation of a Stefan Problem with Application to Cell Thawing

Technology / Case number: #24616
Allan Myerson / Richard Braatz / Qihang Zhang / Moo Sun Hong / Ajinkya Vikram Pandit / Prakitr Srisuma / George Barbastathis
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

Engineering Immune Checkpoint Blockade Nanobody-STINGTM Fusion Protein As A Versatile Treatment For Solid Tumor Cancers

Technology / Case number: #24323
Yanpu He / Shengnan Huang / Angela Belcher
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Improved Treatment for Organ Regeneration and Blocking Scar Formation

Technology / Case number: #25302
Ioannis Yannas
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Using Cross-Dressing to Enhance Anti-Tumor Immune Responses

Technology / Case number: #21679
Stefani Spranger / Ellen Duong
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Enhanced Endogenous Recombination for Gene Therapy and Genetic Engineering

Technology / Case number: #20008M
Guoping Feng / Jonathan Wilde / Tomomi Aida / Martin Wienisch / Qiangge Zhang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Gastric-Resident Devices for Gram-level Drug Delivery

Technology / Case number: #20379JQ
Carlo Giovanni Traverso / Andrew Bellinger / Tyler Grant / Malvika Verma / Taylor Bensel / Daniel Minahan / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

1. Methods for in Vitro Evolution of Constructs Derived from Viruses. 2. Five Mutations Derived from the in Vitro Evolution. 3. Seventeen constructs from the five mutations.

Technology / Case number: #20395H
Ron Weiss / Yingzhong Li / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

PROTAC Derivatives with Functional Handles for Chemical Conjugation/Modification

Technology / Case number: #20788J
Jeremiah Johnson / Yivan Jiang / Hung Nguyen / Alexandre Detappe / Irene Ghobrial / Michael Agius / Aiden Wang
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

filtered: 186 results

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