PROTAC Derivatives with Functional Handles for Chemical Conjugation/Modification
Invention type: Technology
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Case number: #20788J
Disclosed multifunctional compounds, conjugates, macromolecules, and polymers that target dysregulated proteins for degradation. Also disclosed are methods of preparation, compositions, kits, and methods of use relating to the degraders.
Researchers
Jeremiah Johnson
/ Yivan Jiang
/ Hung Nguyen
/ Alexandre Detappe
/ Irene Ghobrial
/ Michael Agius
/ Aiden Wang
Departments: Department of Chemistry, Chemistry
Technology Areas: Chemicals & Materials: Catalysis & Synthesis, Polymers / Therapeutics: Small Molecules
Impact Areas: Healthy Living
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proteolysis targeting chimeric molecules (protacs) with functional handles and uses thereof
United States of America | Published application | 0
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