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Glucose Valve and Other Metabolite Valves

Technology / Case number: #12369
Tae Moon / Kevin Solomon / Kristala L Jones Prather
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Transcriptional Engineering of Lactobacillus for Improved Lactic Acid Tolerance and Productivity at Low pH

Technology / Case number: #12783
Gregory Stephanopoulos / Daniel Klein-Marcuschamer
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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An Information-Theoretic Approach for Analyzing Chromatin State Models

Technology / Case number: #17666
Manolis Kellis / Wouter Meuleman
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
Tyler Jacks / Leah Schmidt / David Feldser
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for Increasing Safety of Embryonic Stem Cells

Technology / Case number: #13769
Clark Colton / Jeffrey Millman
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods for Enhanced Production of Cardiomyocytes From Embryonic Stem Cells

Technology / Case number: #12777
Clark Colton / Amanda Diienno / Jeffrey Millman / Daryl Powers
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods of Controlled Self-Renewal and Differentiation of Intestinal Stem Cells

Technology / Case number: #15728J
Robert Langer / Marc Succi / Xiaolei Yin / Jeffrey Michael Karp
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Microbial Production of 3,4-Dihydroxybutyrate (DHBA) and 3-Hydroxybutyrolactone (3-HBL) from Glucose

Technology / Case number: #14595
Kristala L Jones Prather / Himanshu Dhamankar / Collin Martin
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Rocco Policarpo / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #12321XE
Shuguang Zhang / Xiumei Wang / Fabrizio Gelain / Akihiro Horii
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Mehmet Yanik / Matthew Angel
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Engineering Microbes and Metabolic Pathways for the Production of Ethylene Glycol from Xylose, Glucose, Carbohydrates and Renewable Resources

Technology / Case number: #15064
Gregory Stephanopoulos / Jose Avalos / Marjan De Mey / Brian Pereira / Deepak Dugar
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Brd4 as a Prognostic Indicator and Modulator of the Cell Response to DNA Damage

Technology / Case number: #15011
Michael Yaffe / Scott Floyd
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method for the Characterization and Differentiation of Material Surfaces Using Compound Responses of Mechanically Driven Cells

Technology / Case number: #17585J
Dick Yue / Xiaoying Zhu / Roland Bouffanais
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Cellular Surface Engineering via Multilayered Polymer Nanostructures

Technology / Case number: #12846
Robert Cohen / Albert Swiston / Darrell J Irvine / Michael F Rubner
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Ultrasonic Method for Measuring Concentrations of Particles, Cells and Islets in Suspension

Technology / Case number: #11886J
Clark Colton / Steven Africk
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Tough, Thermoreversible Hydrogels from the Arrested Phase Separation of Elastin-Like Polypeptides: Simple, Injectable, Biocompatible Substrates for the Engineering of Load-Bearing Tissues

Technology / Case number: #17430
Bradley D. Olsen / Reginald Avery / Matthew Glassman
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Genomic Editing with Site- Specific Retrotransposons

Technology / Case number: #25220
Omar Abudayyeh / Christopher Fell / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Synthetic Nanotube Antibody for Selective Molecular Recognition

Technology / Case number: #14090
Michael S. Strano / Jingqing Zhang / Daniel Heller / Paul Barone / Jong Ho Kim
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Single-Walled Carbon Nano-Tube/Chitosan Hydrogel Array for the Label-Free, Optical Detection of Protein-Protein Interactions

Technology / Case number: #14201
Michael S. Strano / Nigel Reuel / Jin Ho Ahn / Paul Barone / Jong Ho Kim
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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