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Fine-Tuning pKa's of Nucleoside Analogs to Increase Mutagenicity; a Strategy to Develop More Potent Lethal Mutagen with Anti-Viral or Anticancer Properties

Technology / Case number: #17657
John M Essigmann / Sam Peng / Vipender Singh / Bogdan I Fedeles / Andrei Tokmakoff
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Splicing-Dependent Transcriptional Gene Silencing or Activation

Technology / Case number: #20890
Christopher B Burge / Ana Fiszbein
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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RNA Scaffolded Wireframe Origami

Technology / Case number: #24153
Mark Bathe / Molly Parsons / Tyson Shepherd
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Mucin-inspired Glycopolymers Can Selectively Kill Vaginal Pathogen Gardnerella Vaginalis Without Impacting Growth of Beneficial Lactobacillus Crispatus

Technology / Case number: #24459
Katharina Ribbeck / Liubov Yakovlieva / Spencer Brucks / Laura L Kiessling / Caroline Werlang / Kelsey Wheeler
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Programmable CRISPR-Responsive Smart Materials

Technology / Case number: #21161JY
James Collins / Peter Q. Nguyen / Angelo Mao / Nicolaas Angenent-Mari / Raphael Gayet / Max English / Luis Soenksen Martinez / Helena de Puig Guixe
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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