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Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids

Technology / Case number: #16016J
Mo Movassaghi / Karen Morrison / Paul Hergenrother / Justin Kim / Nicolas Boyer
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Inhalable Nanosensors with Volatile Reporters for Rapid Pathogen Identification in Respiratory Infections

Technology / Case number: #20307HL
Rod Kunz / Melodi Anahtar / Leslie Chan / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Multilayer Porous Hydrogel for Robust Sensing of Macromolecules with Florescent Carbon Nanotube Sensors

Technology / Case number: #15892
Michael S. Strano / Nigel Reuel
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living
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Develop New Lethal Mutagens for Viral Diseases

Technology / Case number: #16089
John M Essigmann / Katherine Silvestre / Deyu Li
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Brian Belmont / Michael Marletta / Jacquin Niles / Stephen Goldfless
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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High-Throughput Corrosion Testing Platform

Technology / Case number: #16470
Krystyn Van Vliet / Matthew Whitfield
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Darrell J Irvine / Dana Al Sulaiman / Sylvain Ladame / Yin Hao Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of a Platform to Noninvasively Image Car T Cells

Technology / Case number: #25905J
Michael Hemann / Julia Froese / Ali Salehi / Taha Rakhshandehroo / Jennifer Rowley / Mohammad Rashidian
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Full-field Optical Coherence Microscopy System Using a Digital Focal Plane Array

Technology / Case number: #24144LJ
Guillermo Tearney / Michael Bradshaw / Osman Ahsen / Matthew Johnson / Joseph Gardecki
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Estimating Contractile Reserve using a Mechanical Circulatory Support Device

Technology / Case number: #25817J
Elazer R Edelman / Jerald Curran / Ahmad El Katerji / Steven Keller
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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System and Method to Predict Exertional Heat Stroke from Torso-Worn Sensor

Technology / Case number: #21970LJ
Jeffrey Palmer / Joseph Seay / Rebecca Fellin / Mark Buller / Lara Weed / Jim Williamson / Brian Telfer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Biomarkers Derived from Neurophysiological Computational Modeling

Technology / Case number: #18088L
Thomas Quatieri / Joseph Perricone / Gregory Ciccarelli / Jim Williamson / Daryush Mehta / Brian Helfer / Christopher Smalt / Jeffrey Palmer / Satrajit Ghosh
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Renewable Bio-Advantaged Plasticizer Generated by Reductive Coupling of Lignin Derived Aromatics

Technology / Case number: #25385J
Yuriy Roman / Zhiming Su / Caroline Hoyt / Jack Twilton / Shannon Stahl / Gregg Beckham
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Noreen Wauford / Breanna DiAndreth
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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RNA-Triggered Protein Cleavage and Applications by the CRISPR Cas7-11-Csx29 Complex

Technology / Case number: #24545J
Omar Abudayyeh / Cian Schmitt-Ulms / Kazuki Kato / Hiroshi Nishimasu / Kaiyi Jiang / Jonathan S. Gootenberg
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Persistent-Mode MRI Magnet Fabricated from Reacted, Monofilamentary MgB2 Wires

Technology / Case number: #16305
Yukikazu Iwasa / Jiayin Ling / Jungbin Song / YoungJae Kim / John Voccio / Juan Bascunan / Seung-Yong Hahn
Technology Areas: Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Ram Sasisekharan / Devin Quinlan / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tissue Stiffness Quantification for Diagnosis and Mapping

Technology / Case number: #17896
Alexander Slocum / William Plummer / Tyler Wortman / Edward Perez
Technology Areas: Biotechnology / Computer Science / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Fine Wire Muscle Interfaces

Technology / Case number: #24876TE
Hugh M Herr / Cameron Taylor
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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