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Polystyrene Coated Magnetic Beads Serving as Raman Reporter for Simultaneous Target Binding and Identification

Technology, Tangible Property / Case number: #25081
Loza Tadesse / Nikiwe Mhlanga / Jongwan Lee / Marissa Morales
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Programmable Lipid Nanoparticle Delivery via Corona Protein Engineering

Technology / Case number: #25165J
Omar Abudayyeh / Alisan Kayabolen / Cian Schmitt-Ulms / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Molecular Time Capsules Enable Transcriptomic Recording in Living Cells

Technology / Case number: #25337
Gene-Wei Li / Dylan McCormick / Jack Rubien / Mirae Parker
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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An Efficient Bioconjugation Technology for Site-Selective Covalent Modification of Antibodies using an Engineered Affinity Peptide

Technology / Case number: #25358
Bradley L. Pentelute / Katsushi Kitahara / Aurelie Rondon / Heemal Dhanjee / Jacob Rodriguez / Andrei Loas
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Machine Learning-guided Whole-Organ Optical Imaging Technique for Non-destructive Identification of Early Pre-Cancer Lesions and Harvesting of Viable Cells from the same for Organoid Culture

Technology / Case number: #25480
Angela Belcher / Vivek Rastogi / Neelkanth Manoj Bardhan
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Programmable Immunostimulation with Structured DNA Nanoparticles

Technology / Case number: #24273H
Darrell J Irvine / Benjamin Read / Eike-Christian Wamhoff / Tyson Moyer / Rebecca Du / Remi Veneziano / Mark Bathe
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Medical Recordkeeping Microneedles

Technology / Case number: #24923
Robert Langer / Yang Liu / Jooli Han / Maria Kanelli / Ana Jaklenec / Fredo Durand (he/him/his)
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Constriction-Minimizing Microfluidic Devices Enabling Co-Culture in Engineered Hydrogels

Technology / Case number: #24723P
Robert Langer / Alice Stanton / Li-Huei Tsai
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Spatial Proteomics using Photocleavable Anchor in Polyelectrolyte Gel

Technology / Case number: #24358HM
Edward Stuart Boyden / Camille Mitchell-Wang
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Customized Passive Prosthetic Feet

Technology / Case number: #24341
Amos Winter / Charlotte Folinus
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Tissue-integrating Neural Interfaces

Technology / Case number: #24351
Polina Anikeeva / Anthony Tabet
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Smooth Flow Control Systems for Embedded Micropumps on Microfluidic Cell Culture Devices

Technology / Case number: #24379
Linda Griffith / Allison Lenhard / David L Trumper
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Stable and Efficient Cell Surface Coupling of Nanoparticles

Technology / Case number: #17836HQ
Darrell J Irvine / Li Tang / Yiran Zheng
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Silk Materials to Deliver PGPR

Technology / Case number: #21588
Benedetto Marelli / Augustine Zvinavashe
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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A Closed-Loop System for Blood Pressure Control

Technology / Case number: #22797J
Emery N Brown / Taylor Baum
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living
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Hybrid Hydrogel to Support 3D Culture of Primary Human Cells

Technology / Case number: #25192
Linda Griffith / Lauren Pruett / Samantha Holt
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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  • Women's Health
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Augmentation of T and B Cell Activation with a Novel Cysteine Protease Linker Sequence

Technology / Case number: #25338
Tyler Jacks / Sean-Luc Shanahan
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Ribozyme-Enhanced RNA Trans-Splicing

Exclusively Licensed Technology / Case number: #25469J
Omar Abudayyeh / Alisan Kayabolen / Cian Schmitt-Ulms / Jonathan S. Gootenberg
Technology Areas: Biotechnology
Impact Areas: Healthy Living

Reconfigurable Multistep Chemical Synthesis System

Technology / Case number: #18563
Klavs F. Jensen / Aaron Bedermann / Kosi Aroh / Dale Thomas / Andrea Adamo / Timothy F Jamison
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future
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Redox-Electrodes for Electrochemically-Controlled Bio-Macromolecule Interaction: Bio-Separations, Heterogeneous Enzyme Immobilization, Protein Purification and Sensing, Among Others

Technology / Case number: #18540
T. Alan Hatton / Xiao Su
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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