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A Signal Inverter Module for RNA Cleavers: Detecting and Evaluating miRNA, Ribozymes, and Ribonucleases

Technology / Case number: #19604
Ron Weiss / Breanna DiAndreth
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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New Genetic Circuit Topologies for High Performance Multi-Input MicroRNA Sensors for Classifying Living Cell State

Technology / Case number: #19534
Ron Weiss / Jin Huh
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Stuart Boyden / Demian Park / Aimei Yang / Kiryl Piatkevich
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Method to Correct Altered Synaptic Signaling in Autism and Intellectual Disability

Technology / Case number: #18383PHJ
Mark Bear / Robert Lefkowitz / Laura Stoppel / Benjamin Auerbach
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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In-Pipe Leak Detection via Multi-Point Close Proximity Scanning

Technology / Case number: #14570KJ
Kamal Youcef-Toumi / Rached Ben-Mansour / Dimitrios Chatzigeorgiou / Stephen Ho / Sanjay Emani Sarma
Technology Areas: Agriculture & Food / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Method of Assessing Uniformity of Periodic Structures Based on the Decay Time of Laser-Generated Acoustic Vibrations

Technology / Case number: #18820J
Keith A Nelson / Rebecca Forrest / Donna Stokes / Jateen Gandhi / Abdelhak Bensaoula / Hyun Shin / Alexei Maznev
Technology Areas: Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Advanced Materials
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Oligomeric Conjugates for siRNA Delivery and Glucose-Responsive Insulins

Technology / Case number: #15977J
Robert Langer / Rosemary Kanasty / Arturo Vegas / Daniel Anderson
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Channel-less Drip Irrigation Emitter

Technology / Case number: #25861
Amos Winter / Julia Howarth / Aditya Avinash Ghodgaonkar
Technology Areas: Agriculture & Food / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Tunneling Nanoelectromechanical Devices for Analog and Digital Switches

Technology / Case number: #16084
Jeffrey Lang / Parag Deotare / Ellen Sletten / Matthew D'Asaro / Farnaz Niroui / Apoorva Murarka / Trisha Andrew / Annie I Wang / Vladimir Bulovic / Timothy Manning Swager / Hae-Seung Lee
Technology Areas: Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Biodegradable Lipids and Formulations for Intramuscular and Systemic Delivery of mRNA

Technology / Case number: #25351J
Daniel Anderson / Kaelan Reed / Akash Gupta / Arnab Rudra
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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In-Band Full-Duplex Antenna with Direction Finding Capability

Technology / Case number: #24517L
Ken Kolodziej / Pierre Dufilie / David Bragdon / William Moulder / Bradley Perry
Technology Areas: Communication Systems / Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World
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Adaptive Volute Geometries for Centrifugal Pumps

Technology / Case number: #21537
Alexander Slocum / Hilary Johnson / Kevin Simon
Technology Areas: Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Procedurally Generated Metamaterials

Technology / Case number: #24891J
Wojciech Matusik / Chris Wojtan / Yi-Lu Chen / Bolei Deng / Bohan Wang / Liane Makatura / Bernd Bickel
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Advanced Materials
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Modular System for Lyophilization

Technology / Case number: #22603
Alexander Slocum / Bernhardt Trout
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Switched Capacitor Energy Buffer Architecture

Technology / Case number: #14953
Steven Leeb / Arthur Chang / Minjie Chen / Khurram Afridi / David J Perreault
Technology Areas: Electronics & Photonics / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Connected World
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All-to-All Connected Ising Machines with Free-Space Optical Interconnects

Technology / Case number: #21178L
William Herzog / Siddhartha Ghosh / Suraj Bramhavar / Jeffrey Chou
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World
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PropDesigner

Technology / Case number: #21700L
Tommy Sebastian / Keegan Quigley / Ryan Fontaine / Peter Sharpe / Joe Belarge / David Maurer
Technology Areas: Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Methods And Compositions For High-Throughput Compressed Screening For Therapeutics

Technology / Case number: #21936RH
No Inventor / Conner Kummerlowe / Benjamin Mead / Alex Shalek
Technology Areas: Computer Science / Therapeutics
Impact Areas: Healthy Living
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Infrastructure-free NLoS Obstacle Detection for Autonomous Cars

Technology / Case number: #22032J
Daniela Rus / Christina Liao / Alexander Amini / Igor Gilitschenski / Felix Naser / Sertac Karaman / Guy Rosman
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Two-Phase Helium Convection Loop For Cryogenic Cooling

Technology / Case number: #22110L
John Ingwersen / John Cummings / Sergey Tolpygo / Lawrence Narkewich / George Haldeman
Technology Areas: Industrial Engineering & Automation
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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