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Fanzors are RNA-Guided Nucleases Encoded in Eukaryotic Genomes

Technology / Case number: #24942
Omar Abudayyeh / Jonathan S. Gootenberg / Justin Lim / Kaiyi Jiang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Ana Jaklenec / Robert Langer / Mina Konakovic Lukovic / Jinbi Tian / Khanh Tran / Amy Lee
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Vikash Pal Singh Chauhan / Robert Langer / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Spring-Loaded Double Pentograph (SLDP) Mechanism for Human Balancing and Weight Support

Technology / Case number: #25811
Ravi Tejwani / Harry Asada
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Method and Apparatus for High Throughput Diagnosis of Diseased Cells With Microchannel Devices

Technology / Case number: #11937
Ken Babcock / Subra Suresh / Scott Manalis / Thomas Burg
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Multi-Dimensionally Encodable Neuron Device based on Two-Dimensional Materials

Technology / Case number: #25704J
Jeehwan Kim / Min Kyu Song / Hyeongseok Jang
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Jooli Han / Tina Huang
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Compact, Planar Transient Grating Spectroscopy System

Technology / Case number: #25473
Michael Short / Jonas Rajagopal / Benjamin Dacus / Angus Wylie
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Liquid Exchange and Positioning of Cellular Entities in a Liquid-air Interface

Technology / Case number: #24928J
Linda Griffith / Georgios Katsikis / Haidong Feng / Joseph Doyle / Scott Manalis
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers
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  • Women's Health
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Targeted Trans-splicing Using CRISPR-Cas Systems

Technology / Case number: #20505ER
Jacob Borrajo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Smart Injection Needle System for Accurate Characterization of Cell Types, Concentrations, and Viability

Technology / Case number: #24367J
Giovanni Traverso / Fangzhou Xia / Kamal Youcef-Toumi / Adam Gierlach / Kewang Nan / Yiyuan Yang / Ming Zhao
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Utilizing a Strategic Blend of Block Copolymers to Control Particle Surface Charge for Enhanced Mucus Transport and Tissue Targeting

Technology / Case number: #25439J
Katharina Ribbeck / Corey Alfred Stevens / Robert Prud'homme / Boris Sevarika / Angela Belcher
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Multi-Waveguide Beam Scanners and Scanning Pattern Methods

Technology / Case number: #26324J
Dirk R Englund / Henry Wen / Matthew Zimmermann
Technology Areas: Biotechnology / Electronics & Photonics / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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Polymeric Core-Shell Particles for Pulsatile Release of HIV Vaccine

Technology / Case number: #26230
Ana Jaklenec / Robert Langer / Maria Kanelli / Behnaz Eshaghi / Amy Lee / Rishi Das / Aki Gurram / Stacey Lin
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Giovanni Traverso / Yunhua Shi / Ameya Kirtane / Grace Junyue Zhong / Daniel Reker / Robert Langer / Hyunjoon Kim / Netra Kamat / James Byrne / Gary Liu
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Amino Acid, Peptide, Polypeptide-Lipids (APPL) Derivatives and Uses Thereof

Technology / Case number: #14910Q
Kevin Love / Arturo Vegas / Delai Chen / Yi Chen / Yizhou Dong / Yunlong Zhang / Akinleye Alabi / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Patient-Specific Benchtop Beating Heart Simulator for Recreating Left Atrial Biomechanics and Hemodynamics for LAA Closure and HFpEF Intervention Testing

Technology / Case number: #25761
Ellen Roche / Keegan Mendez / Manisha Singh
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction from Cellulosic Materials

Technology / Case number: #15695
Mitchell Tai / Gregory Stephanopoulos
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
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Hand Exoskeleton System for Data Collection

Technology / Case number: #26180
Branden Romero / Pulkit Agrawal / Edward Adelson / Haoshu Fang / Arthur Hu
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Strategy for Installing Hydrophobic Chains Plus Phosphorus Ligands onto MOFs

Technology / Case number: #25160
Mircea Dinca / Valiallah Hosseininasab / Nathan Gin
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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