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Self Actuating Systems for Retention and Electrical Stimulation in the Gastrointestinal Tract

New
Technology / Case number: #20292JQ
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / David Dellal / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Solid Formulations with Ultra-High Drug Loading

New
Technology / Case number: #19446J
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / Robert Langer
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Multi-Pronged Self-Orienting Millimeter-Scale Actuator for Drug Delivery

New
Technology / Case number: #21169JQ
Giovanni Traverso / Alex Abramson / Robert Langer / Michael Williams / Jacob Wainer
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Injectable, Thermogelling, Prolonged-Release Hydrogel Formulations for CPG-ODNs

New
Technology / Case number: #26051J
Giovanni Traverso / Ameya Kirtane / Robert Langer / Avik Som / Jan-Georg Rosenboom / Eric Wehrenberg-Klee / Stephen Linderman
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Acid-Gas Regeneration Process for Ex-Situ Carbon Mineralization of Magnesium Silicate Minerals

New
Technology / Case number: #26097
Yogesh Surendranath / Anatole Borisov
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future, Advanced Materials
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A Double Pinch Criterion for Optimization of Regenerative Rankine Cycles: Powerplant Operation and Simmulation/Optimization Software Modeling Strategies

New
Technology, Software / Case number: #14875
Alexander Mitsos / Hussam Zebian
Technology Areas: Energy & Distribution / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Climate Stabilization, Sustainable Future
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N-Heterocyclic Imine as a Potential Redox-Active Sorbent for Electrochemical CO2 Separation

New
Technology / Case number: #26251
Betar Gallant / Fang-Yu Kuo / Glen Junor / Akachukwu Obi
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Decoupling CO2 Capture and Electrochemical Sorbent Regeneration with Nanofiltration

New
Technology / Case number: #26244
Simon Rufer / Tal Joseph / Zara Aamer / Kripa K Varanasi
Technology Areas: Energy & Distribution / Environmental Engineering / Sensing & Imaging
Impact Areas: Climate Stabilization, Sustainable Future
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

New
Technology / Case number: #25731J
Ralph Weissleder / Akash Gupta / Kaelan Reed / Riddha Das / Christopher Garris / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods, Materials, and Systems for Valorization of Gypsum and Phosphogypsum based Feedstocks

New
Technology / Case number: #26410
Camden Hunt / Amilton Botelho Junior / Yet-Ming Chiang
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future
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Intermediate Temperature Steam Electrolysis In a Molten Salt Electrolyte

New
Technology / Case number: #26155
Yogesh Surendranath / Rui Zeng / India Cox
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future, Advanced Materials
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Self-Righting Systems, Methods, and Related Components

New
Technology / Case number: #20706JQ
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / Robert Langer
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Fanzors are RNA-Guided Nucleases Encoded in Eukaryotic Genomes

Technology / Case number: #24942
Omar Abudayyeh / Jonathan S. Gootenberg / Justin Lim / Kaiyi Jiang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Ana Jaklenec / Robert Langer / Mina Konakovic Lukovic / Jinbi Tian / Khanh Tran / Amy Lee
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Innate Immune Modulating RNA Vaccines

Technology / Case number: #26293H
B.j. Kim / Darrell J Irvine
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Jooli Han / Tina Huang
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Prolonged-Release Hydrogel Formulations of Toll-Like Receptor Agonists for Intratumoral Injection to Increase Immunotherapy Response

Technology / Case number: #23215J
Giovanni Traverso / Robert Langer / Arijit Basu / Avik Som / Jan-Georg Rosenboom / Gabrielle Ndakwah / Eric Wehrenberg-Klee / Umar Mahmood
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Targeted Trans-splicing Using CRISPR-Cas Systems

Technology / Case number: #20505ER
Jacob Borrajo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Jesse C Patterson / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Yuting Huang
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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