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Single-shot 16-fold Expansion Microscopy (16ExM)

Technology / Case number: #24859MH
Edward Boyden / Laura Kiessling / Tay Won Shin / Shiwei Wang / Yixi Liu / Harley Yoder
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Ultrastructural Membrane Expansion Microscopy

Technology / Case number: #25088HM
Edward Boyden / Tay Won Shin
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Clockwise Learning Task

Technology / Case number: #25128M
Georgios Papageorgiou / Ann Graybiel
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Engineered Synthetic IRES with Improved and Robust Translation in Circular RNA

Technology / Case number: #25300YJ
James Collins / Katherine Ilia / Shiva Razavi / Kehan Zhang / Xiaoyu Chen / Makoto Lalwani / Yu Li / Nayoung Kim
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Reconstituted Lipoprotein Particles to Rescue Lipid Defects in the Alzheimer's Brain

Technology / Case number: #25445P
Li-Huei Tsai / Rebecca Pinals
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Ultra-High Resolution Mapping of 3D Genome Structure using Region Capture Micro-C

Technology / Case number: #24967
Anders Sejr Hansen / Viraat Goel / Miles Huseyin
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Optimized Alum-Anchored HIV Env Immunogens

Technology / Case number: #24972HJ
Kristen Rodrigues / Christopher Cottrell / Jon Steichen / William Schief / Darrell Irvine
Technology Areas: Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipids and Formulations for Intramuscular, In Vitro, and Ex Vivo Transfection of mRNA

Technology / Case number: #23969J
Arnab Rudra / Akash Gupta / Kaelan Reed / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A Diagnostic and Treatment Prediction Toolkit for Bipolar Disorder based on Polymorphisms in CPG2 Regulatory Domains

Technology / Case number: #23591P
Baovi Vo / Elly Nedivi
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Photothermal Trap for Ice Mitigation

Technology / Case number: #19805
Susmita Dash / Jolet De Ruiter / Kripa Varanasi
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Near and Shortwave Infrared Polymethine Dyes

Technology / Case number: #19474
Ellen Sletten / Justin Caram / Timothy Swager
Technology Areas: Diagnostics / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Method for Point-of-use Testing for Bacteriological Water Contamination in Resource-Limited Environments

Technology / Case number: #19080
Rohit Karnik / Emily Hanhauser / Michael Bono / Chintan Vaishnav / Sydney Beasley / Anastasios Hart
Technology Areas: Biotechnology / Diagnostics / Environmental Engineering / Sensing & Imaging
Impact Areas: Healthy Living
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Scalable and Safe Quantum Dot Precursor

Technology / Case number: #20834
Daniel Franke / Matthias Ginterseder / Moungi Bawendi
Technology Areas: Chemicals & Materials / Diagnostics / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Device and Method for Isolation and Detection of Target Cells/Particles from Complex Background Matrices

Technology / Case number: #20847
Rohit Karnik / Emily Hanhauser / Michael Bono / Mary Strawser
Technology Areas: Diagnostics
Impact Areas: Healthy Living
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Near Infrared Fluorescent Biosensors for Steroid Hormones

Technology / Case number: #21434
Michael Strano / Michael Lee / Naveed Bakh / Song Wang
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Quantitative Ultra-sensitive Detection of Biological Species

Technology / Case number: #21467
Suchol Savagatrup / Kosuke Yoshinaga / Jie Li / Zachary Nelson / Cassandra Zentner / Timothy Swager
Technology Areas: Agriculture & Food / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Fluorescence-based detection of protein aggregation and fiber optic-based benchtop instrument

Technology / Case number: #21556
Michael Strano / Daichi Kozawa / Xun Gong / Daniel Salem / Sooyeon Cho / Freddy Nguyen
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Extending Fluorescent Assays In Vivo for Biomedical Sensing: Wavelength Modulation Spectroscopy

Technology / Case number: #22003
Michael Strano / Volodymyr Koman / Naveed Bakh
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Device and Method for Isolation and Detection of Soluble or Particulate Analytes from Complex Background Matrices

Technology / Case number: #23246
Rohit Karnik / Krithika Ramchander / Emily Hanhauser / Mary Strawser / Chun Man Chow
Technology Areas: Agriculture & Food / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Antibody-Free Rapid Detection of SARS-CoV-2 Proteins Using Corona Phase Molecular Recognition (CoPhMoRe)

Technology / Case number: #23605
Michael Strano / Xun Gong / Sooyeon Cho / Xiaojia Jin / Sungyun Yang / Jianqiao Cui
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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