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1. Methods for in Vitro Evolution of Constructs Derived from Viruses. 2. Five Mutations Derived from the in Vitro Evolution. 3. Seventeen constructs from the five mutations.

Technology / Case number: #20395H
Ron Weiss / Yingzhong Li / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Anti-Human KLRB1 Monoclonal Antibodies and Uses Thereof

Technology / Case number: #21645J
Kai Wucherpfennig / Byong Ha Kang / Nathan Mathewson / Karl Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Single-Cell Density as A Biomarker for Drug Sensitivity

Technology / Case number: #23741J
Keith Ligon / Richard Wu / Teemu Miettinen / Sarah Ishamuddin / Kin-Hoe Chow / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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High-Throughput and High-Precision Measurement of Single-Cell Density

Technology / Case number: #23740
Richard Wu / Teemu Miettinen / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Split Intein-based Selection for Modified Peptide Binders to SARS-CoV-2 Spike Protein

Technology / Case number: #22502
Christopher Voigt / Emerson Glassey / Andrew King
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Low Power Battery and Signaling System

Technology / Case number: #25211J
Carlo Giovanni Traverso / Adam Gierlach / James McRae / Yeseul Jeon / Ian Ballinger / Anantha Chandrakasan
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems / Energy & Distribution
Impact Areas: Healthy Living, Connected World
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Methods for Machine-Learning Guided Protein Design

Technology / Case number: #25084
Omar Abudayyeh / Jonathan Gootenberg / Kaiyi Jiang / Matteo Di Bernardo
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Redox-Electrodes for Electrochemically-Controlled Bio-Macromolecule Interaction: Bio-Separations, Heterogeneous Enzyme Immobilization, Protein Purification and Sensing, Among Others

Technology / Case number: #18540
Trevor Hatton / Xiao Su
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Polymer Based Solid-State Solar Thermal Fuels

Technology / Case number: #18399
Jeffrey Grossman / David Zhitomirsky
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Efficient Absorption for Electrochemically Based Carbon Dioxide Capture

Technology / Case number: #19871
Trevor Hatton / Sahag Voskian / Miao Wang / Ryan Shaw
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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Vertically-Aligned Insulator Nanomaterial as Structural Separator for Multifunctional Composite Energy Storage

Technology / Case number: #19840
Brian Wardle / Luiz Henrique Acauan / Yue Zhou
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Small PbS/CdS Core-Shell Quantum Dot Hole Transport Material for Improvement of Low Temperature, Solution Processed Planar Perovskite Solar Cells

Technology / Case number: #18081
Whitney Hess / Moungi Bawendi
Technology Areas: Chemicals & Materials / Electronics & Photonics / Energy & Distribution
Impact Areas: Sustainable Future, Advanced Materials
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Complex Liquid Crystal Droplets

Technology / Case number: #21760
Cassandra Zentner / Alberto Concellon Allueva / Timothy Swager
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Bifunctional Downconversion and Passivation Layer for Silicon Solar Cells Employing a Nitride Dielectric

Technology / Case number: #20272
Tony Wu / Markus Einzinger / Marc Baldo
Technology Areas: Chemicals & Materials / Electronics & Photonics / Energy & Distribution
Impact Areas: Sustainable Future, Advanced Materials
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Electrochemical Flow System for Portable Hydrogen Peroxide Generation

Technology / Case number: #20225
Trevor Hatton / Yogesh Surendranath / Sahag Voskian / Alexander Murray
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Multi-Stage Adsorption-Based Atmospheric Water Harvesting

Technology / Case number: #21788
Evelyn Wang / Alina LaPotin / Yang Zhong
Technology Areas: Energy & Distribution / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Material Joining via Micro-Jet Locking

Technology / Case number: #21802
David Veysset
Technology Areas: Chemicals & Materials / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Modular Integrated Gas High Temperature Nuclear Reactor

Technology / Case number: #21873
Enrique Velez Lopez / William Stewart
Technology Areas: Energy & Distribution
Impact Areas: Uncharted Frontiers
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TRAV-005 (Needles) 62/795,857

Technology / Case number: #22144J
Selim Olcum / Robert Kimmerling / David Weinstock / Scott Manalis
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Low-Loss Shielded Radio-Frequency Inductor

Technology / Case number: #23074J
Charles Sullivan / Rachel Yang / Roderick Bayliss / Alex Hanson / David Perreault
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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