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Synthesis of Covalent Protein Dimers that can Inhibit MYC-Driven Transcription

Technology / Case number: #23305WJ
Bradley Pentelute / Isaac Klein / Carly Schissel / Sebastian Pomplun / Andrei Ioan Loas / Jacob Rodriguez / Muhammad Jbara / Ann Boija / Susana Hawken / Charles Li / Stephen Buchwald
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Folded Lightweight Aperture Precision System (FLAPS)

Technology / Case number: #19330
Kerri Cahoy / Christian Haughwout / Derek Barnes / Maxim Khatsenko / James Clark
Technology Areas: Communication Systems / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Uncharted Frontiers, Connected World
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Satellite Tracking System Using Amateur Telescope and Star Camera for Portable Optical Ground Station

Technology / Case number: #18849
Kerri Cahoy / Kathleen Riesing / Hyosang Yoon
Technology Areas: Communication Systems
Impact Areas: Uncharted Frontiers, Connected World
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Predicting Native Language from Gaze

Technology / Case number: #19818
Yevgeni Berzak / Boris Katz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Connected World
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A Platform for Continuous Directed Evolution in Human Cells

Technology / Case number: #19909
Matthew Shoulders / Louis Papa / Christopher Moore / Chet Berman / Samuel Hendel
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Compositions and Methods to Increase Muscular Strength Without Exercise

Technology / Case number: #19768
Roger Kamm / Vivek Sivathanu
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Potent Agelastatin Derivatives as Modulators for Cancer Invasion and Metastasis

Technology / Case number: #19505J
Mohammad Movassaghi / Rachel Buchsbaum / Alyssa Antropow / Kun Xu
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Diazene Directed Modular Synthesis of Oligocyclotryptamines

Technology / Case number: #18747
Mohammad Movassaghi / Petra Lindovska
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
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Enhancing tumor immunogenicity with Hsp90 inhibition

Technology / Case number: #20303WHJ
Luke Whitesell / Alexander Jaeger / Sandro Santagata / Tyler Jacks / Susan Lindquist
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Layer-by-Layer Nanoparticles for Cytokine Therapy in Cancer Treatment

Technology / Case number: #20027H
Erik Dreaden / Mariane Melo / Antonio Barberio / Santiago Correa Echavarria / Talar Tokatlian / Darrell Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Methods and Compositions for Increasing Sensitivity of Cancer Cells to Glutaminase Inhibitors and Applications to Cancer Therapy

Technology / Case number: #19305
Matthew Vander Heiden / Dan Gui / Alexander Muir / Laura Danai
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Methods for Gene Delivery with Papillomaviruses

Technology / Case number: #21704
Omar Abudayyeh / Jonathan Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Structured DNA Nanoparticle Platform for Protein- and Peptide-based Vaccines

Technology / Case number: #20929H
Mark Bathe / Remi Veneziano / Rebecca Du / Tyson Moyer / Eike-Christian Wamhoff / Benjamin Read / Darrell Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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