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Replacing Synthetic Fertilizers by Engineering Cereal-Associated Nitrogen-Fixing Bacteria to Release Urea

Technology / Case number: #25157
Christopher Voigt / Phillip Clauer
Technology Areas: Agriculture & Food / Biotechnology
Impact Areas: Sustainable Future
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Advanced Architectures and Operating Principles for Electrochemical Neuro-Modulation

Technology / Case number: #20280J
Jongyoon Han / Matthew Flavin / Daniel Freeman
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Intranasal amphiphile-protein conjugate vaccine

Technology / Case number: #23991H
Darrell J Irvine / Brittany Hartwell
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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High-Resolution Long-Term Wearable Ultrasound Devices

Exclusively Licensed Technology / Case number: #24013
Xuanhe Zhao / Chonghe Wang / Xiaoyu Chen
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living

Activatable Antimicrobial Peptides and Uses Thereof

Technology / Case number: #24024H
Sangeeta Bhatia / Chayanon Ngambenjawong
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Fabrication of Polymeric Microneedles with Hollow and Porous Tips via a Simple Micromolding Process Assisted by Ionic Salts

Technology / Case number: #24093
Benedetto Marelli / Doyoon Kim
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Advanced Materials
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A Multi-Pathway Reporter System that Interrogates Repair of DNA Double-Strand Breaks with Applications for Diagnosis and Therapeutic Treatment of Cancer and Neurodegenerative Diseases

Technology / Case number: #25444
Michael Yaffe / Alex Kruswick
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Epoxides for Multimodal Detection of Biomolecules by Expansion Microscopy

Technology / Case number: #24137HM
Edward Stuart Boyden / Yi Cui
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Compositions of Polyhydroxylated Benzophenones and Methods of Treatment of Neurodegenerative Disorders

Technology / Case number: #17855PJQ
Li-Huei Tsai / Ping-Chieh Pao / Debasis Patnaik / Stephen Haggarty
Technology Areas: Therapeutics
Impact Areas: Healthy Living
Labels
  • Alzheimer's Therapeutics
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Small Molecules Suppressors of APOE Gene Expression and Cerebral Vascular Amyloid Pathology

Technology / Case number: #22991P
Li-Huei Tsai / Joel Blanchard
Technology Areas: Therapeutics
Impact Areas: Healthy Living
Labels
  • Alzheimer's Therapeutics
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Small Molecules to Improve Myelination in Alzheimer's Disease and APOE4 Carriers

Technology / Case number: #23168P
Li-Huei Tsai / Matheus Victor / Audrey Effenberger / Djuna von Maydell / Leyla Akay / Jose Davila Velderrain / Joel Blanchard / Manolis Kellis
Technology Areas: Therapeutics
Impact Areas: Healthy Living
Labels
  • Alzheimer's Therapeutics
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Using Anti-Inflammatory Drugs To Enhance The Neuroprotective Effects Of Non-Invasive Gamma Stimulation

Technology / Case number: #23402P
Li-Huei Tsai / Julia Bonner / Vanesa Fernandez Avalos / Chinnakkaruppan Adaikkan
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
Labels
  • Alzheimer's Therapeutics
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Lipid Nanoparticles for Drug Delivery to Microglia in the Brain

Technology / Case number: #23156P
Robert Langer / William Ralvenius / Julia Bonner / Jason Andresen / Joel Blanchard / Owen Fenton / Li-Huei Tsai
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
Labels
  • Alzheimer's Therapeutics
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Multicellular Integrated Brain Tissue for Investigation and Therapeutic Discovery in Neurological Diseases

Technology / Case number: #22618P
Robert Langer / Adele Bubnys / Alice Stanton / Joel Blanchard / Li-Huei Tsai
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
Labels
  • Alzheimer's Therapeutics
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Use of Choline Supplementation as Therapy for APOE4-Related Disorders

Technology / Case number: #20957WPJ
Li-Huei Tsai / Greg Sienski / Priyanka Narayan / Julia Bonner / Yuan-Ta Lin
Technology Areas: Therapeutics
Impact Areas: Healthy Living
Labels
  • Alzheimer's Therapeutics
License

Reconfigurable Multistep Chemical Synthesis System

Technology / Case number: #18563
Klavs F. Jensen / Aaron Bedermann / Kosi Aroh / Dale Thomas / Andrea Adamo / Timothy F Jamison
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future
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Redox-Electrodes for Electrochemically-Controlled Bio-Macromolecule Interaction: Bio-Separations, Heterogeneous Enzyme Immobilization, Protein Purification and Sensing, Among Others

Technology / Case number: #18540
T. Alan Hatton / Xiao Su
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Task Specific Ionic Liquids for Electrochemically Mediated Scrubbing of CO2

Exclusively Licensed Technology / Case number: #18537
T. Alan Hatton / Sahag Voskian / Paul Brown
Technology Areas: Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
Labels
  • CO2 Capture

Robust Anti-Icing Polymer Coatings

Technology / Case number: #18517
Robert Cohen / Dayong Chen / Gareth McKinley
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Topology Optimization with Microstructures

Technology / Case number: #18489
Bo Zhu / Melina Skouras / Desai Chen / Wojciech Matusik
Technology Areas: Industrial Engineering & Automation
Impact Areas: Sustainable Future
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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