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Artificially Engineered Protein Hydrogels to Mimic Nucleoporin Selective Gating

Technology / Case number: #17166
Bradley D. Olsen / Minkyu Kim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Box Knot Strain Sensor

Technology / Case number: #25179
Rachel Bellisle / Katya Arquilla / Amy Huynh / Nicole McGaa
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Non-Surgical Biomedical Implants

Technology / Case number: #25352TE
Deblina Sarkar / Shubham Yadav
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Glucose- Responsive Microgels for Closed Loop Insulin Delivery

Technology / Case number: #15057J
Zhen Gu / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Superconducting Parametric Amplifier Neural Network

Technology / Case number: #21125L
Alexander Wynn
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Long-Term Stability of Hygroscopic Hydrogels by Preventing Metal Ion-Mediated Degradation

Technology / Case number: #25804
Xuanhe Zhao / Chad Wilson / Carlos Diaz Marin / Gang Chen
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Programable Fluidic Chip

Technology / Case number: #25589
Alfredo Alexander-Katz / Guillermo Hernandez-Mendoza
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Frameshift Suppressor tRNAs for Canonical Amino Acids

Technology / Case number: #21418TREJ
Kevin Esvelt / Erika Alden DeBenedictis / Ahmed Badran
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Advanced Materials
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Improving Statistical Model-Based Speech Enhancement with Deep Neural Networks

Technology / Case number: #21028L
Bengt Borgstrom / Michael Brandstein / Robert Dunn
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World, Advanced Materials
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Ingestible Electronics Integrated with Flexible Measurement Electrodes for Gastrointestinal Bioelectric Sensing

Technology / Case number: #23241J
Giovanni Traverso / Robert Langer / Sean You / So-Yoon Yang / Adam Gierlach / George Selsing
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Endovascular Injectable Stents for Cardiovascular Drug Delivery

Technology / Case number: #22578J
Giovanni Traverso / Sahab Babaee / Mazen Albaghdadi / Mohammed Chowdhury
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Analysis and Design of a Membrane-based Triggering Mechanism for Ingestible Devices

Technology / Case number: #22043
Giovanni Traverso / Graham Arrick / Torben Sebastia Last
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Giovanni Traverso / Hen Wei Huang / SeungHo Lee / Saurav Maji / Peter Chai / Tom Kerssemakers / Ian Ballinger / Anantha Chandrakasan
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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Small Molecule Modulators of the Androgen Receptor

Technology / Case number: #19771
Angela Koehler / Nicholas Struntz / David Freeman / Shelby Doyle / Andre Richters
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Max Binders Modulators of Myc-Mediated Transcription with Potential Use for Cancer Therapy

Technology / Case number: #18257
Angela Koehler / Eric Stefan / Francisco Caballero Gonzalez / Dylan Neel / Helen Evans / Nicholas Struntz / Andrew Chen
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Macro-Devices for Ultra-Long Residence and Large-Dose Drug Delivery in Stomach

Technology / Case number: #20938JQ
Giovanni Traverso / Robert Langer / Sahab Babaee / Simo Pajovic / Jiuyun Shi
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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