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RNA-based Logic Circuits with RNA Binding Proteins, Aptamers and Small Molecules

Exclusively Licensed Technology / Case number: #16631HJ
Darrell J Irvine / Kei Endo / Hirohide Saito / Tyler Wagner / Jacob Becraft / Katie Bodner / Tasuku Kitada / Velia Siciliano / Maria Hottelet Foley / Liliana Wroblewska / Ron Weiss
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Method for Noninvasive Extraction of Fetal Cardiac Signals from Maternal Abdominal Recordings

Exclusively Licensed Technology / Case number: #13469J
Gari Clifford / Mohammed Shamsollahi / Christian Jutten / Reza Sameni
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living

'Inverse Patterning' Process for 3D Multi-Compartmental Micro-Organization of Multiple Cell Types

Exclusively Licensed Technology / Case number: #15455H
Sangeeta Bhatia / Kelly Stevens
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

In Situ Sequencing of Expanded Biological Specimens

Non-Exclusively Licensed Technology / Case number: #17496TEYJQ
Edward Stuart Boyden / Shahar Alon / Evan Daugharthy / Adam Marblestone / Paul Tillberg / Fei Chen / George Church
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

Probing and Manipulating Cell Functions Through Intracellular Delivery

Exclusively Licensed Technology / Case number: #17162HJ
Robert Langer / Sophia Liu / Megan Heimann / George Hartoularos / Shirley Mao / Gregory Szeto / Armon Sharei / Ulrich Von Andrian / Pamela Basto / Siddharth Jhunjhunwala / Darrell J Irvine / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

High-Throughput Platform for In-Vivo Sub-Cellular Screens on Vertebrate Larvae

Exclusively Licensed Technology / Case number: #14114
Mehmet Yanik / Cody Gilleland / Carlos Pardo Martin / Tsung-Yao Chang / Steven Charles Wasserman
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living

Stochastic Barcoding Method for Single-Cell Tracking

Exclusively Licensed Technology / Case number: #16514H
Darrell J Irvine / Marc Castellarnau / Gregory Szeto / J. Christopher Love / Joel Voldman
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Superbiocompatible Polymers and Hydrogels for Reducing Foreign Body Reactions

Exclusively Licensed Technology / Case number: #18000JQ
Robert Langer / Volkan Yesilyurt / Omid Veiseh / Joshua Doloff / Arturo Vegas / Daniel Anderson
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

System for the Concentration of Beer

Exclusively Licensed Technology / Case number: #17368
John Lienhard / Ronan McGovern
Technology Areas: Chemicals & Materials / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Healthy Living, Sustainable Future

Variable Interscan Time Analysis System

Exclusively Licensed Technology / Case number: #19459
James Fujimoto / Woo Jhon Choi / Stefan Ploner / Eric Moult
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living

Antibody Brush Prodrug Conjugates

Exclusively Licensed Technology / Case number: #23260
Jeremiah A. Johnson / Samantha Kristufek / Yutong Dai / Landon Kilgallon / Valerie Lensch / Bin Liu / Wencong Wang / Peyton Shieh / Hung Nguyen
Technology Areas: Therapeutics
Impact Areas: Healthy Living

Concepts and Devices for Electrokinetic Extraction and Delivery of Macromolecules for Intact Biological Systems

Exclusively Licensed Technology / Case number: #16669
Kwanghun Chung / Jae Cho / Evan Murray / Kimberly Ohn / Sung-Yon Kim
Technology Areas: Biotechnology
Impact Areas: Healthy Living

Protein Retention Expansion Microscopy

Non-Exclusively Licensed Technology / Case number: #18129TE
Edward Stuart Boyden / Chih-Chieh (Jay) Yu / Paul Tillberg / Fei Chen
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

Dry Double-sided Tape for Instant Tough Bonding of Wet Tissues and Devices

Exclusively Licensed Technology / Case number: #20888
Xuanhe Zhao / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Tissue Fabrication by Selective Deletion within a Multicellular Construct

Exclusively Licensed Technology / Case number: #22098HJQ
Christopher Chen / Hyun Ho Song / Amanda Chen / Arnav Chhabra / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living

Gamma Entrainment Binds Higher Order Brain Regions, Improves Cognitive Function, and offers Neuroprotection

Exclusively Licensed Technology / Case number: #20070P
Li-Huei Tsai / Chinnakkaruppan Adaikkan
Technology Areas: Therapeutics
Impact Areas: Healthy Living

Methods and Compositions for Ameliorating or Inhibiting Decline in Memory or Intelligence or Improving Same

Exclusively Licensed Technology / Case number: #12090Q
Richard Wurtman / Lisa Teather / Judith Wurtman
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living

Arbitrary Targeted Deep Focused Neural Modulation

Non-Exclusively Licensed Technology / Case number: #17436TEQ
David Bono / Nir Grossman / Edward Stuart Boyden
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

A Fully Synthetic Nanoparticle Vaccine Platform Technology Composed of Dendrimer-Based Lipidoid Nanomaterials, Self-Amplifying Ribose Nucleic Acids and Polyethylene Glycol

Exclusively Licensed Technology / Case number: #17873WJH
Robert Langer / David Canner / Jasdave Chahal / Omar Khan / Daniel Anderson / Hidde Ploegh / Tyler Jacks
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Novel Classes of Channelrhodopsin

Exclusively Licensed Technology, Tangible Property / Case number: #15253TQJE
Gane Wong / Yongku Cho / Nathan Klapoetke / Edward Stuart Boyden / Brian Chow
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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