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Synthesis and Anti-cancer Activity of Communesin Alkaloids

Technology / Case number: #21462
Mohammad Movassaghi / Matthew Pompeo / Jaime Cheah
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Synthesis of Potent Epidithiodiketopiperazines Designed for Facile Derivatization

Technology / Case number: #21469
Mohammad Movassaghi / Joshua Payette / Jaime Cheah / Chase Olsson / Tony Scott
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Use of Synthetic ETPs in Reversing Cancer Chemoresistance

Technology / Case number: #22888J
Mohammad Movassaghi / Vikas Sukhatme / Mo Motamedi / Junichi Hanai
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Small Molecules Suppressors of APOE Gene Expression and Cerebral Vascular Amyloid Pathology

Technology / Case number: #22991P
Li-Huei Tsai / Joel Blanchard
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Compounds, Compositions, and Methods of Macrocyclic Depsipeptide Antibiotics

Technology / Case number: #23104
Mohammad Movassaghi / Bradley Pentelute / Carly Schissel / Kyan D'Angelo
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Heme-binding Small Peptide

Technology / Case number: #23132
Graham Walker / Siva Sankari Iyer Mani Sankaran / Vigneshbabu Musuri Periasamy
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Small Molecules to Improve Myelination in Alzheimer's Disease and APOE4 Carriers

Technology / Case number: #23168P
Li-Huei Tsai / Manolis Kellis / Joel Blanchard / Jose Davila Velderrain / Leyla Akay / Djuna von Maydell / Audrey Effenberger / Matheus Victor
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Using Anti-Inflammatory Drugs To Enhance The Neuroprotective Effects Of Non-Invasive Gamma Stimulation

Technology / Case number: #23402P
Li-Huei Tsai / Chinnakkaruppan Adaikkan / Vanesa Fernandez / Julia Bonner
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Adhesive, Injectable Hydrogels for Local Therapy Delivery to Brain Tumors

Technology / Case number: #24170J
Natalie Artzi / Michelle Dion / Dahis Daniel
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Compositions for the Conditional Delivery of Macromolecules and Combination Therapeutics

Technology / Case number: #24492H
Chayanon Ngambenjawong / Edward Tan / Qian Zhong / Sangeeta Bhatia
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Drinkable, Tough Hydrogels for Gastrointestinal Applications

Technology / Case number: #24642J
Carlo Giovanni Traverso / Robert Langer / Gary Liu / Matthew Pickett
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Modulating Oncogenic Transcriptional Dysregulation with Small Molecule Chimeric Degraders of Cyclin-Dependent Kinase 9

Technology / Case number: #24831
Angela Koehler / Mohammed Toure / Keisuke Motoyama
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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An Efficient Bioconjugation Technology for Site-Selective Covalent Modification of Antibodies using an Engineered Affinity Peptide

Technology / Case number: #25358
Bradley Pentelute / Andrei Ioan Loas / Jacob Rodriguez / Heemal Dhanjee / Aurelie Rondon / Katsushi Kitahara
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Tandem Peptide Approaches for Delivery to Gram-Negative Bacteria

Technology / Case number: #19017H
Ester Kwon / Leslie Chan / Sangeeta Bhatia
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Locally Delivered Therapeutics and Combinations for Expedited Passage of Urinary Stones

Technology / Case number: #19454J
Michael Cima / Xiang Li / Brian Eisner
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Multi-Targeted, Tunable, Sustained Delivery of Drugs and Other Payloads to Charged Avascular Tissues

Technology / Case number: #21303
Yamini Krishnan / Alan Grodzinsky
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Purification of Substances Using CO2 Sub-and Super-Critical Fluid Chromatography

Technology / Case number: #19742
William Dalzell / John Moses / Veronica Wilson / Mariya Layurova / Tony Elian / Truong Cai / John MacKay / Clark Colton
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Sustainable Future
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Dysferlinopathy Compounds

Technology, Tangible Property / Case number: #22496
Mohan Viswanathan / Eric Williams / Kana Tominaga / Naoomi Tominaga / Leonard Guarente
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Targeting Lung Microbiota and its Responding Immune Pathways for Lung Cancer Treatment

Technology / Case number: #20602HRJ
Paul Blainey / Chengcheng Jin / Georgia Lagoudas / Tyler Jacks
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Nanoparticle Conjugates of Highly Potent Toxins

Technology / Case number: #19222
Paiman Ghoroghchian / Ruogu Qi
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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