Li-Huei Tsai

Director, Picower Institute & Picower Professor

Department
DLC Heads Science
Technology Areas
Biotechnology: Biomedical Devices & Systems, Sensors & Monitoring, Synthetic Biology, Tissue Engineering, DNA & RNA Editing / Sensing & Imaging: Acoustics, Chemical & Radiation Sensing / Therapeutics: Small Molecules, Nucleic Acids, Proteins & Antibodies, Cell Based Therapy, Regenerative Medicine / Computer Science: Bioinformatics / Drug Discovery and Research Tools: Genomics & Proteomics, Cell Interrogation, Cell Culture, Cell Lines & Organoids, Animal Models / Chemicals & Materials: Polymers, Nanotechnology & Nanomaterials, Catalysis & Synthesis / Diagnostics: Assays / Drug Delivery: Microparticles & Nanoparticles
Impact Areas

Technologies

Using a Genetically Modified Human IPS Line to Screen for Drugs that Prevent or Treat Alzheimer's Disease

Technology / Case number: #26292P
Li-Huei Tsai / TaeHyun Kim / Leyla Akay / Matheus Victor / Masayuki Nakano
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Disrupted in Schizophrenia 1 (DISC-1) Interacts with the Wnt Signaling Pathway and Regulates Neurogenesis

Technology / Case number: #12654HBJ
Li-Huei Tsai / Stephen Haggarty / Yingwei Mao / Jon Madison
Technology Areas: Chemicals & Materials / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
License

Branched Chain Fatty Acids Have Immune-Modulatory Effects

Technology / Case number: #25569P
Li-Huei Tsai / Lorenzo Bozzelli
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Inhibition of Histone Deacetylase 2 Facilitates Extinction of Aversive Memory

Technology / Case number: #13759HBJRQ
Li-Huei Tsai / Stephen Haggarty / Jisong Guan / Edward Holsen / Florence Wagner / Johannes Graff
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Epigenetic Mechanisms Re-Establish Access to Long-Term Memory After Neuronal Loss

Technology / Case number: #12467HPBJ
Weiping Tang / Andre Fischer / Li-Huei Tsai / Stephen Haggarty / Stuart Schreiber
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Methods and Compositions of Matter for Activating Class I Histone Deacetylases (HDACs) for Treatment of Human Disease

Technology / Case number: #14951PJHQ
Li-Huei Tsai / Stephen Haggarty / Ling Pan / Debasis Patnaik
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Combined 40Hz Stimulation and Dexmedetomidine Therapy for Alzheimers Disease and Neuronal Degeneration

Technology / Case number: #25176PJ
Li-Huei Tsai / Emery N Brown / Diane Chan / Jordan Harrod / Oluwaseun Johnson-Akeju
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

In Vitro Human Blood Brain Barrier

Technology / Case number: #19918P
Li-Huei Tsai / Joel Blanchard
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Reconstituted Lipoprotein Particles to Rescue Lipid Defects in the Alzheimer's Brain

Technology / Case number: #25445P
Li-Huei Tsai / Rebecca Pinals
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Gamma Entrainment using Sensory Stimuli Alleviate Cognitive Deficits and Neuroinflammation Induced by Chemotherapy Agents

Technology / Case number: #22066P
Li-Huei Tsai / TaeHyun Kim
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

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