Paul Barone

Co-Director, Biomanufacturing Program

Department
Center for Biomedical Innovation
Technology Areas
Biotechnology: Biomanufacturing, Synthetic Biology, DNA & RNA Editing, Sensors & Monitoring / Drug Delivery: Vectors & Virus like Particles / Therapeutics: Nucleic Acids, Proteins & Antibodies, Cell Based Therapy, Regenerative Medicine / Chemicals & Materials: Nanotechnology & Nanomaterials / Drug Discovery and Research Tools: Antibodies, Genomics & Proteomics / Sensing & Imaging: Optical Sensing, Chemical & Radiation Sensing

Background and Experience

Dr. Barone has been at the Massachusetts Institute of Technology’s Center for Biomedical Innovation (CBI) since 2010 where he is currently the Director of the Consortium on Adventitious Agent Contamination in Biomanufacturing (CAACB) a pre-competitive biopharmaceutical industry consortium focused on identifying and sharing best practices to mitigate the risk of adventitious agent contamination in biopharmaceutical manufacturing. Dr. Barone is also the Co-Director of Biomanufacturing@MIT-CBI, where he manages a variety of sponsored research activities related to biopharmaceutical manufacturing, including the development of novel analytical technologies for the rapid assessment of protein product quality, the development of a process for the continuous production of viral vectors, and the development of an online course on the principles of cell therapy manufacturing.

Technologies

Single-Walled Carbon Nanotube Based Hydrogels for In Vivo Glucose Detection

Technology / Case number: #13588
Michael S. Strano / Paul Barone / Jingqing Zhang / Jin Ho Ahn / Ardemis Boghossian / Rene Ortiz Garcia / Hyeonseok Yoon
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
License

A Synthetic Nanotube Antibody for Selective Molecular Recognition

Technology / Case number: #14090
Michael S. Strano / Jong Ho Kim / Paul Barone / Daniel Heller / Jingqing Zhang
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

A Single-Walled Carbon Nano-Tube/Chitosan Hydrogel Array for the Label-Free, Optical Detection of Protein-Protein Interactions

Technology / Case number: #14201
Michael S. Strano / Jong Ho Kim / Paul Barone / Jin Ho Ahn / Nigel Reuel
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
License

Encapsulation Forms and Modulation Chemistries for Ratiometric, Internally Calibrated Near Infrared Fluorescent Single-Walled Carbon Nanotube Sensor for Reversible Glucose Detection

Technology / Case number: #14887
Michael S. Strano / Paul Barone / Jin Ho Ahn / Kyungsuk Yum / Thomas McNicholas
Technology Areas: Chemicals & Materials / Sensing & Imaging
License

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