Angela Koehler

Associate Professor
Department
Department of Biological Engineering
Technology Areas
Biotechnology: Biomanufacturing, Biomedical Devices & Systems / Therapeutics: Cell Based Therapy, Small Molecules, Proteins & Antibodies / Drug Discovery and Research Tools: Cell Lines & Organoids, Genomics & Proteomics / Diagnostics: Assays / Drug Delivery: Microparticles & Nanoparticles / Chemicals & Materials: Catalysis & Synthesis, Polymers
Impact Areas
Healthy Living, Advanced Materials, Uncharted Frontiers

Pioneering research into next-generation molecular probes, transcending traditional boundaries in cancer genomics and precision medicine.

Background and Experience

Angela Koehler is an Associate Professor in the Department of Biological Engineering at MIT and an intramural member of the David H. Koch Institute for Integrative Cancer Research at MIT. She is also an Institute Member of the Broad Institute and a Founding Member of the MIT Center for Precision Cancer Medicine. Her research group aims to discover and develop functional small-molecule probes of targets emerging from patient-based genomics, including targets deemed recalcitrant to small molecule drug discovery efforts, such as transcription factors, RNA-binding proteins or cytokines. Selected probes may be developed into imaging agents, diagnostic tools, or therapeutic leads.

Technologies

Novel Small Molecule Modulators of Myb-Mediated Transcription with Potential Use for Cancer Therapy

Technology / Case number: #22044
Angela Koehler / Becky Leifer / Florian Kabinger / Brice Curtin / Jasmin Kruell
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Sign up for technology updates

Sign up now to receive the latest updates on cutting-edge technologies and innovations.

Sign Up