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Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Rocco Policarpo / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Glycan-Receptor Binding of the Novel Influenza A Virus H7N9 Hemagglutinin

Technology / Case number: #16359
Rahul Raman / Nathan Stebbins / Kannan Tharakaraman / Akila Jayaraman / Ram Sasisekharan
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Selective Nitric Oxide Optical Sensors Based on Near Infrared Fluorescent Single Walled Carbon Nanotubes (SWNT)

Technology / Case number: #13445
Michael S. Strano
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Multi-Parameter Data-Set for Detection of Thrombotic Risk

Technology / Case number: #13105J
Elazer R Edelman / Kumaran Kolandaivelu
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Split Peroxidases for Detection of Protein-Protein Interactions

Technology / Case number: #16082
Alice Ting / Jeffrey Martell
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Chemotactic Magnetic Bead Chain Chemical Probe

Technology / Case number: #15619
Joshua Steimel / Charles Sing / Hsieh Chen / Alfredo Alexander-Katz
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Synthesis and Anticancer Activity of Agelastatin Alkaloids

Technology / Case number: #16512J
Mo Movassaghi / Paul Hergenrother
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Formulations for Stabilizing Lactobacillus and Bifidobacterium Strains

Technology / Case number: #25723J
Giovanni Traverso / Isaac Tucker / Kimberley Biggs / Mairead Heavey / Samantha Bozorgzadeh / Matt Murphy / Christina Karavasili
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Cystic Fibrosis Correction with Programmable Genomic Editing

Technology / Case number: #24666
Omar Abudayyeh / Christopher Fell / Matthew Yarnall / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Device for Trapping Hepatitis C Viral Particles in Ultra Low Concentrations

Technology / Case number: #14418J
Michael Cima / Fredric Gordon / Sebastian Flacke / Christopher Wald / Hongye Ye / Gregory Ekchian / Vincent Liu / Christophoros Vassiliou
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Porphyrin-based Sensors for Fluorescence and MRI

Technology / Case number: #12381
Stephen J Lippard / Alan Pradip Jasanoff
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Covalently Functionalized Hydrogels on Oxygen Permeable Membranes for Stable, Scalable, and Xeno Free Growth of Undifferentiated Human Embryonic Stem Cells

Technology / Case number: #16162
Clark Colton / Amanda Diienno / Anna Coclite / Karen Gleason
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Extra Cellular Matrix Proteins and Cancer

Technology / Case number: #15501JHR
Richard Hynes / Kenneth Tanabe / Karl Clauser / Alexandra Naba / Steven Carr
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Cytosolically-Active Peroxidases as Reporters for Electron Microscopy

Technology / Case number: #15128
Alice Ting / Jeffrey Martell
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Methods for Cell Separation and Cytometry Based on Directed Cell Rolling on Patterned Substrates

Technology / Case number: #12899
Robert Langer / Suman Bose / Rohit N Karnik / Jeffrey Michael Karp / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Method for the Detection of Anticoagulants in Plasma and Whole Blood

Technology / Case number: #19252J
James Fox / Charles Vanderburg / Pavan Bendapudi / Galit H. Frydman / Mehmet Toner / Ronald Tompkins
Technology Areas: Diagnostics
Impact Areas: Healthy Living
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Inhalable Nanosensors with Volatile Reporters for Rapid Pathogen Identification in Respiratory Infections

Technology / Case number: #20307HL
Rod Kunz / Melodi Anahtar / Leslie Chan / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Sangeeta Bhatia
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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