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A Micro Physiological Model for ALS

Technology / Case number: #20857
Roger Kamm / Tatsuya Osaki / Sebastien Uzel
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Persistent Carbene Monolayers on Silicon Substrates

Technology / Case number: #18755
Jeremiah A. Johnson / Aleksandr Zhukhovitskiy
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Advanced Materials
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Microfluidic Device for the 3D and Compartmentalized Coculture of Neuronal and Muscle Cells, with Functional Force Readout

Technology / Case number: #18042
Roger Kamm / Sebastien Uzel
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Implantable Active Coil-based Transducers (ImpACTs) for Minimally-Invasive Biophysical Imaging

Technology / Case number: #20183
Alan Pradip Jasanoff / Aviad Hai / Virginia Spanoudaki
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Electronics & Photonics
Impact Areas: Healthy Living
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A Platform for Continuous Directed Evolution in Human Cells

Technology / Case number: #19909
Matthew D. Shoulders / Samuel Hendel / Chet Berman / Christopher Moore / Louis Papa
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Concepts and Methods for Controlling Chemical Reaction Kinetics and Interaction Time in Large Systems

Technology / Case number: #18377
Kwanghun Chung / Jae Cho / Evan Murray
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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High-Throughput Native Context Mapping of the Regulatory Genome

Technology / Case number: #18012JQ
David K Gifford / Richard Sherwood / Nisha Rajagopal
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Drug Delivery Based on Bistable Membrane

Technology / Case number: #17624
Michael Cima
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Protein Corona Phase Molecular Recognition (CoPhMoRe)

Technology / Case number: #18316
Michael S. Strano / Gili Bisker Raviv
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living
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Continuous Freeze-Drying of Pharmaceuticals and Biopharmaceuticals in Unit Doses

Technology / Case number: #19494J
Bernhardt Trout / Capozzi Carlo / Roberto Pisano
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method to Distinguish and Analyze White Blood Cells in the Presence of Red Blood Cells

Technology / Case number: #18889
Shivang Dave / Jason Tucker-Schwartz
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Electromechanical Lysis of Bacterial Pathogens using Ion Concentration Polarization

Technology / Case number: #19035
Jongyoon Han / Minseok Kim
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Atherofluidics-on-Chip

Technology / Case number: #18096
Joel Voldman / Sarvesh Varma
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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PNA Amphiphile Adjuvant Delivery Vehicles

Technology / Case number: #18878H
Darrell J Irvine / Eric Dane
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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M13 Phage Assembly System for Optimal Blood Trafficking, Tumor Penetration, and Passage Across the Blood Brain Barrier

Technology / Case number: #19438
Angela Belcher / Fred Lam / Uyanga Tsedev
Technology Areas: Drug Delivery / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Compositions and Methods for Treating and Preventing Obesity

Technology / Case number: #18085J
Manolis Kellis / Jan Korbel / Melina Claussnitzer
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Multiplexed Specific Metalloprotease Activity Measurements

Technology / Case number: #19425DE
Steven Robert Tannenbaum / Evan Chiswick / Ravindra Kodihalli / Christi Cook / Caroline Chopko Ahrens / Miles Miller / Douglas Lauffenburger / Linda Griffith
Technology Areas: Biomaterials & Bioelectronics / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Open-Ended, Dicer-Cleavable Concatemeric siRNA Generated by Rolling Circle Transcription

Technology / Case number: #18076
Paula Hammond / Kevin Shopsowitz / Connie Wu
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of Multi-Specific Antibody-Serum Albumin Fusion Proteins Targeting Multiple Human and Murine CXC (ELR+) Chemokines

Technology / Case number: #19355JQ
Karl Dane Wittrup / Andrew Luster / Alessandro Angelini
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley L. Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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